Featured Publications
Orbital and Periorbital Dysmorphology in Untreated Pfeiffer Syndrome
Lu X, Forte AJ, Allam O, Park KE, Wilson A, Alperovich M, Steinbacher DM, Tonello C, Alonso N, Persing JA. Orbital and Periorbital Dysmorphology in Untreated Pfeiffer Syndrome. Plastic & Reconstructive Surgery 2022, 149: 731e-742e. PMID: 35171849, DOI: 10.1097/prs.0000000000008928.Peer-Reviewed Original ResearchConceptsPfeiffer syndrome patientsMonths of ageOrbital cavity volumeSyndrome patientsPfeiffer patientsSphenoid boneGlobe volumeAnterior positioningCLINICAL QUESTION/LEVELNormal control subjectsYears of ageSoft tissue volumeControl subjectsSignificant hypoplasiaPatientsBone volumePfeiffer syndromeVisual impairmentBony orbitAnteroposterior lengthMaxillaVolumetric analysisAgeMonthsMaterialise softwareAirway Growth in Preoperative Patients with Crouzon Syndrome
Lu X, Forte AJ, Park KE, Allam O, Smetona J, Alperovich M, Steinbacher DM, Tonello C, Alonso N, Persing JA. Airway Growth in Preoperative Patients with Crouzon Syndrome. Facial Plastic Surgery & Aesthetic Medicine 2021, 23: 191-197. PMID: 33577380, DOI: 10.1089/fpsam.2020.0441.Peer-Reviewed Original ResearchConceptsYears of ageNasal airway volumeAirway volumeCrouzon syndromePharyngeal airwayCross-sectional areaAirway cross-sectional areaObstructive sleep apneaMonths of agePreoperative patientsSleep apneaMaximal constrictionAirway developmentAirway growthTomography scanAge subgroupsCT scanPatientsSyndromeCrouzon patientsNatural historyAgeNormal dimensionsAirwayMaterialise softwareGrowth patterns of the airway in Crouzon syndrome patients with different types of cranial vault suture synostosis
Lu X, Forte AJ, Wilson A, Park KE, Allam O, Alperovich M, Steinbacher DM, Tonello C, Alonso N, Persing JA. Growth patterns of the airway in Crouzon syndrome patients with different types of cranial vault suture synostosis. International Journal Of Oral And Maxillofacial Surgery 2020, 50: 924-932. PMID: 33384236, DOI: 10.1016/j.ijom.2020.11.023.Peer-Reviewed Original ResearchConceptsAirway volumeCrouzon syndrome patientsYears of ageNasal airwaySyndrome patientsCrouzon patientsPharyngeal airwayCrouzon syndromeSuture synostosisNasopharyngeal airway volumePharyngeal airway volumeNasal airway volumeType IComputed tomography scanType IIIBilateral coronal synostosisAirway compromiseRespiratory difficultyControl subjectsTomography scanAirwayPatientsPharyngeal volumeSagittal synostosisCoronal synostosisMorphological Basis for Airway Surgical Intervention in Apert Syndrome
Lu X, Forte AJ, Park KE, Allam O, Alperovich M, Steinbacher DM, Tonello C, Alonso N, Persing JA. Morphological Basis for Airway Surgical Intervention in Apert Syndrome. Annals Of Plastic Surgery 2020, 87: 59-64. PMID: 34133365, DOI: 10.1097/sap.0000000000002601.Peer-Reviewed Original ResearchConceptsApert syndrome patientsPharyngeal airway volumeComputed tomography scanSyndrome patientsApert syndromeAirway volumeSurgical interventionTomography scanNasal cavityPreoperative computed tomography scansAirway volume changesAge-related subgroupsYears of ageMonths of agePosition of maxillaGrowth of mandibleAirway compromiseNasopharyngeal airwayPharyngeal airwayNasal airwayIntergonial widthSyndromeAirwayPatientsAnteroposterior length
2020
Amelanotic melanoma of the head and neck: analysis of tumor characteristics from the National Cancer Database
Huayllani MT, Boczar D, Saleem HY, Spaulding AC, Bagaria SP, Lu X, Kassis S, Perdikis G, Forte AJ. Amelanotic melanoma of the head and neck: analysis of tumor characteristics from the National Cancer Database. International Journal Of Dermatology 2020, 60: 347-351. PMID: 33040374, DOI: 10.1111/ijd.15243.Peer-Reviewed Original ResearchConceptsNational Cancer DatabaseTumor characteristicsAmelanotic melanomaBreslow depthCancer DatabaseMitotic countCommon malignant melanomaPresence of ulcerationEarly disease stagesYears of ageRare subtypeDisease stageCutaneous melanomaMalignant melanomaMelanomaOlder ageAMHNPatientsNeckStatistical differenceUlcerationAgeHeadCountLymphNational Analysis of Patients With Ulcerated Melanoma in the United States
Boczar D, Sisti A, Restrepo DJ, Huayllani MT, Manrique OJ, Lu X, Spaulding AC, Bagaria SP, Parker AS, Forte AJ. National Analysis of Patients With Ulcerated Melanoma in the United States. Anticancer Research 2020, 40: 1055-1058. PMID: 32014953, DOI: 10.21873/anticanres.14042.Peer-Reviewed Original ResearchConceptsUlcerated melanomaNational Cancer DatabaseNon-white patientsNon-white raceZip codesYears of agePatient disparitiesPatient demographicsMelanoma patientsTumor characteristicsMale sexUnfavorable prognosisCancer DatabaseHigher oddsLower oddsPatientsMelanomaUlcerationFacility characteristicsLower educationOddsLow incomeEducation levelUrban countiesPresent study
2019
Temporal Evaluation of Craniofacial Relationships in Apert Syndrome
Lu X, Forte AJ, Sawh-Martinez R, Wu R, Cabrejo R, Gabrick K, Steinbacher DM, Alperovich M, Alonso N, Persing JA. Temporal Evaluation of Craniofacial Relationships in Apert Syndrome. Journal Of Craniofacial Surgery 2019, 30: 317-325. PMID: 30358751, DOI: 10.1097/scs.0000000000004836.Peer-Reviewed Original ResearchConceptsYears of ageApert syndromeNasal spineComputed tomography scanMaxillary planeAnterior nasal spineMonths of ageApert syndrome patientsPosterior nasal spineSella-nasion planeTomography scanSyndrome patientsAge subgroupsAnatomic relationshipsSyndromeFacial deformityAngulation changeFrankfort horizontal planeCranial base lengthMonthsIntracellular regulatory mechanismsCraniofacial malformationsAgeDeformityMaterialize software
2018
Normal angulation of skull base in Apert syndrome
Lu X, Forte AJ, Sawh-Martinez R, Wu R, Cabrejo R, Steinbacher DM, Alperovich M, Alonso N, Persing JA. Normal angulation of skull base in Apert syndrome. Journal Of Cranio-Maxillofacial Surgery 2018, 46: 2042-2051. PMID: 30391086, DOI: 10.1016/j.jcms.2018.09.026.Peer-Reviewed Original ResearchConceptsAnterior cranial baseApert syndromeCranial base lengthSkull baseSevere craniofacial deformitiesPosterior cranial base lengthYears of ageMonths of ageUnoperated patientsCT scanAnterior cranial base lengthCranial base angleLate infancySyndromeAge rangeCraniofacial deformitiesCranial baseDeformityAdditive effectSkull vaultMonthsAngulationSignificant changesAgeBase length