2022
Cytomegalovirus proteins, maternal pregnancy cytokines, and their impact on neonatal immune cytokine profiles and acute lymphoblastic leukemogenesis in children.
Wiemels JL, Wang R, Zhou M, Hansen H, Gallant R, Jung J, Mancuso N, De Smith AJ, Metayer C, Kogan SC, Ma X. Cytomegalovirus proteins, maternal pregnancy cytokines, and their impact on neonatal immune cytokine profiles and acute lymphoblastic leukemogenesis in children. Haematologica 2022, 107: 2266-2270. PMID: 35638549, PMCID: PMC9425315, DOI: 10.3324/haematol.2022.280826.Peer-Reviewed Original ResearchMeSH KeywordsChildCytokinesCytomegalovirusCytomegalovirus InfectionsFemaleHumansInfant, NewbornPrecursor Cell Lymphoblastic Leukemia-LymphomaPregnancy
2016
In utero cytomegalovirus infection and development of childhood acute lymphoblastic leukemia
Francis SS, Wallace AD, Wendt GA, Li L, Liu F, Riley LW, Kogan S, Walsh KM, de Smith AJ, Dahl GV, Ma X, Delwart E, Metayer C, Wiemels JL. In utero cytomegalovirus infection and development of childhood acute lymphoblastic leukemia. Blood 2016, 129: 1680-1684. PMID: 27979823, PMCID: PMC5364339, DOI: 10.1182/blood-2016-07-723148.Peer-Reviewed Original ResearchConceptsAcute lymphoblastic leukemiaCMV infectionCytomegalovirus infectionLymphoblastic leukemiaChildhood acute lymphoblastic leukemiaUtero cytomegalovirus infectionCongenital CMV infectionCommon childhood cancerActive viral transcriptionBone marrow specimensNon-Hispanic whitesTiming of infectionNewborn blood samplesEtiologic roleRisk factorsChildhood cancerHealthy controlsHigh prevalenceMarrow specimensLeukemia blastsBlood samplesPrenatal originEtiologic agentInfectionHispanic children