2018
Association Between Prostate Magnetic Resonance Imaging and Observation for Low-risk Prostate Cancer
Leapman MS, Wang R, Park HS, Yu JB, Weinreb JC, Gross CP, Ma X. Association Between Prostate Magnetic Resonance Imaging and Observation for Low-risk Prostate Cancer. Urology 2018, 124: 98-106. PMID: 30107188, DOI: 10.1016/j.urology.2018.07.041.Peer-Reviewed Original ResearchConceptsLow-risk prostate cancerProstate magnetic resonance imagingMagnetic resonance imagingProstate cancerDefinitive treatmentPCa diagnosisEnd Results-Medicare databaseResonance imagingMultivariable logistic regression analysisPropensity scoreDiagnosis of PCaUse of MRIConditional logistic regression modelsLogistic regression analysisLogistic regression modelsInitial managementMultivariable analysisGreater oddsPatientsSocioeconomic statusDiagnosisHigher likelihoodRegression analysisDemographic factorsCancer
2012
HLA-DP genetic variation, proxies for early life immune modulation and childhood acute lymphoblastic leukemia risk
Urayama KY, Chokkalingam AP, Metayer C, Ma X, Selvin S, Barcellos LF, Wiemels JL, Wiencke JK, Taylor M, Brennan P, Dahl GV, Moonsamy P, Erlich HA, Trachtenberg E, Buffler PA. HLA-DP genetic variation, proxies for early life immune modulation and childhood acute lymphoblastic leukemia risk. Blood 2012, 120: 3039-3047. PMID: 22923493, PMCID: PMC3471514, DOI: 10.1182/blood-2012-01-404723.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultCase-Control StudiesChildChild, PreschoolFemaleGenetic Predisposition to DiseaseGenetic VariationGenotypeHispanic or LatinoHLA-DP alpha-ChainsHLA-DP beta-ChainsHumansImmunologic FactorsInfantMalePrecursor Cell Lymphoblastic Leukemia-LymphomaPrognosisRisk FactorsWhite PeopleYoung AdultConceptsAcute lymphoblastic leukemiaImmune modulationChildhood acute lymphoblastic leukemiaChildhood acute lymphoblastic leukemia riskAcute lymphoblastic leukemia riskEarly immune modulationHuman leukocyte antigen (HLA) genesLowest exposure categoryLogistic regression analysisEtiology of childhoodNon-Hispanic whitesHLA-DPB1 geneRace/ethnicityInfectious exposureLymphoblastic leukemiaImmune mechanismsExposure categoriesHispanic ethnicityLeukemia riskGenetic susceptibility lociHLA-DPA1Immune systemHispanic childrenRegression analysisEvidence of interaction
2008
Heterocyclic aromatic amine pesticide use and human cancer risk: Results from the U.S. Agricultural Health Study
Koutros S, Lynch CF, Ma X, Lee WJ, Hoppin JA, Christensen CH, Andreotti G, Freeman LB, Rusiecki JA, Hou L, Sandler DP, Alavanja MC. Heterocyclic aromatic amine pesticide use and human cancer risk: Results from the U.S. Agricultural Health Study. International Journal Of Cancer 2008, 124: 1206-1212. PMID: 19058219, PMCID: PMC2904521, DOI: 10.1002/ijc.24020.Peer-Reviewed Original ResearchConceptsAgricultural Health StudyColon cancerPesticide applicatorsBladder cancerCancer incidenceHealth StudyIntensity-weighted lifetime exposure daysEtiology of bladderLifetime exposure daysRate ratioLicensed pesticide applicatorsPoisson regression analysisHuman cancer riskProximal cancersIncident cancerProspective cohortLymphohematopoietic cancersExcess riskCancer riskExposure daysLifetime exposureCancerRegression analysisRiskHeterocyclic aromatic amines
2007
Dichlorvos exposure and human cancer risk: results from the Agricultural Health Study
Koutros S, Mahajan R, Zheng T, Hoppin JA, Ma X, Lynch CF, Blair A, Alavanja MC. Dichlorvos exposure and human cancer risk: results from the Agricultural Health Study. Cancer Causes & Control 2007, 19: 59-65. PMID: 17943454, PMCID: PMC2822646, DOI: 10.1007/s10552-007-9070-0.Peer-Reviewed Original ResearchConceptsDDVP exposurePesticide applicatorsRate ratioAgricultural Health Study cohortCumulative exposure daysHealth Study cohortSmall excess riskConfidence intervalsLicensed pesticide applicatorsPoisson regression analysisLymphohematopoietic cancersStudy cohortIncident casesPotential confoundersExcess riskProstate cancerFamily historyCancer riskExposure daysCancerComprehensive questionnaireRegression analysisCohortExposureRisk