HGG-11. GERMLINE GENETIC PREDISPOSITION TO PEDIATRIC GLIOMA
Muskens I, Walsh K, Zhang C, de Smith A, Morimoto L, Ma X, Wiemels J. HGG-11. GERMLINE GENETIC PREDISPOSITION TO PEDIATRIC GLIOMA. Neuro-Oncology 2019, 21: ii89-ii89. PMCID: PMC6477444, DOI: 10.1093/neuonc/noz036.105.Peer-Reviewed Original ResearchPediatric glioma patientsGBM patientsGene burden testingGlioma patientsPediatric gliomasPediatric brain tumorsPathogenic germline mutationsPopulation-based sampling strategyGermline genetic predispositionCancer predisposition genesRare germline variantsWhole-exome sequencingTreatment strategiesPractice guidelinesBest practice guidelinesBrain tumorsGenetic predispositionCancer-related genesPatientsTP53 mutationsTP53 variantsGlioma riskFrameshift mutationBlood spotsNonsense mutation