2018
Selection of patients with myelodysplastic syndromes from a large electronic medical records database and a study of the use of disease-modifying therapy in the United States
Ma X, Steensma DP, Scott BL, Kiselev P, Sugrue MM, Swern AS. Selection of patients with myelodysplastic syndromes from a large electronic medical records database and a study of the use of disease-modifying therapy in the United States. BMJ Open 2018, 8: e019955. PMID: 30037860, PMCID: PMC6059277, DOI: 10.1136/bmjopen-2017-019955.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAnemiaAzacitidineDatabases, FactualDecitabineElectronic Health RecordsEnzyme InhibitorsFemaleHematinicsHumansImmunologic FactorsIron Chelating AgentsLenalidomideMaleMiddle AgedMultivariate AnalysisMyelodysplastic SyndromesProportional Hazards ModelsRecurrenceRetrospective StudiesThalidomideTreatment OutcomeUnited StatesConceptsDisease-modifying therapiesErythropoiesis-stimulating agentsElectronic medical record databaseMyelodysplastic syndromeMedical record databasePatient characteristicsTreatment patternsGE Centricity Electronic Medical Records databaseRecord databaseLow baseline hemoglobin levelMultivariable Cox regression modelsLarge electronic medical record databaseBaseline hemoglobin levelAbsence of comorbiditiesFirst-line treatmentMajority of patientsSelection of patientsCox regression modelIron chelation therapyAgent azacitidineMore comorbiditiesHemoglobin levelsMale genderClinical trialsChelation therapy
2016
Factors affecting time to active therapy (AT) among patients (pts) with myelodysplastic syndromes (MDS) in a US electronic medical records (EMR) database.
Scott B, Kiselev P, Fliss A, Huang M, Steensma D, Ma X, Swern A, Sugrue M. Factors affecting time to active therapy (AT) among patients (pts) with myelodysplastic syndromes (MDS) in a US electronic medical records (EMR) database. Journal Of Clinical Oncology 2016, 34: e18548-e18548. DOI: 10.1200/jco.2016.34.15_suppl.e18548.Peer-Reviewed Original ResearchActive therapyMyelodysplastic syndromeUS electronic medical record databaseElectronic medical record databaseMedical record databaseRecord databasePatientsSyndromeTherapy
2015
Use of an Electronic Medical Record (EMR) Database to Identify a Real-World Cohort of US Patients (Pts) with Myelodysplastic Syndromes (MDS)
Ma X, Swern A, Kiselev P, Fliss A, Lu J, Scott B, Steensma D, Sugrue M. Use of an Electronic Medical Record (EMR) Database to Identify a Real-World Cohort of US Patients (Pts) with Myelodysplastic Syndromes (MDS). Blood 2015, 126: 3319. DOI: 10.1182/blood.v126.23.3319.3319.Peer-Reviewed Original ResearchDiagnosis of MDSICD-9-CM codesReal-world cohortMyelodysplastic syndromeActive treatmentEMR databaseFinal cohortInitial cohortCelgene CorporationBaseline characteristicsSupportive careSupportive treatmentTreatment patternsClinical trialsSEER programInclusion criteriaReal-world clinical practiceElectronic medical record databaseClinical Modification codesPopulation-based surveillanceEnd Results ProgramPrimary care physiciansCancer outcomes researchBone marrow aspirateClinical practice data