2024
High ambient temperature in pregnancy and risk of childhood acute lymphoblastic leukaemia: an observational study
Rogne T, Wang R, Wang P, Deziel N, Metayer C, Wiemels J, Chen K, Warren J, Ma X. High ambient temperature in pregnancy and risk of childhood acute lymphoblastic leukaemia: an observational study. The Lancet Planetary Health 2024, 8: e506-e514. PMID: 38969477, PMCID: PMC11260908, DOI: 10.1016/s2542-5196(24)00121-9.Peer-Reviewed Original ResearchConceptsRisk of childhood acute lymphoblastic leukemiaChildhood acute lymphoblastic leukemiaAcute lymphoblastic leukemiaLymphoblastic leukemiaLatino childrenNon-Latino white childrenAssociated with risk of adverse pregnancy outcomesCalifornia Cancer RegistryRisk of acute lymphoblastic leukemiaCalifornia birth recordsRisk of adverse pregnancy outcomesPre-pregnancy periodAssociated with riskBayesian meta-regressionNational Institutes of HealthCancer RegistryCases of childhood acute lymphoblastic leukemiaNational Center for Advancing Translational SciencesAdverse pregnancy outcomesAcute lymphoblastic leukemia casesInstitutes of HealthInvestigation of mechanistic pathwaysBirth recordsGestational weeks 8Pre-pregnancy
2023
Birth characteristics and risk of Ewing sarcoma
Wiemels J, Wang R, Feng Q, Yee A, Morimoto L, Metayer C, Ma X. Birth characteristics and risk of Ewing sarcoma. Cancer Causes & Control 2023, 34: 837-843. PMID: 37335392, PMCID: PMC10460323, DOI: 10.1007/s10552-023-01737-4.Peer-Reviewed Original ResearchConceptsBirth characteristicsEwing's sarcomaConclusionsThis population-based studyDisease riskMultivariable logistic regression modelNon-Hispanic white subjectsPopulation-based seriesPopulation-based studySignificant risk factorsMetastatic Ewing sarcomaEwing's sarcoma casesMinimal selection biasLogistic regression modelsYear of birthPurposeThe incidenceFetal growthRisk factorsSarcoma casesLower riskSarcomaMultiethnic populationBirth recordsWhite subjectsGenetic susceptibilityPredisposition allelesOutdoor artificial light at night, air pollution, and risk of childhood acute lymphoblastic leukemia in the California Linkage Study of Early-Onset Cancers
Zhong C, Wang R, Morimoto L, Longcore T, Franklin M, Rogne T, Metayer C, Wiemels J, Ma X. Outdoor artificial light at night, air pollution, and risk of childhood acute lymphoblastic leukemia in the California Linkage Study of Early-Onset Cancers. Scientific Reports 2023, 13: 583. PMID: 36631468, PMCID: PMC9834257, DOI: 10.1038/s41598-022-23682-z.Peer-Reviewed Original ResearchConceptsAcute lymphoblastic leukemiaRisk of childhoodEarly-onset cancersLymphoblastic leukemiaBirth recordsChildhood acute lymphoblastic leukemiaNon-Hispanic white childrenHispanic childrenCalifornia Cancer RegistryEtiology of childhoodOutdoor artificial lightOutdoor ALANHighest tertileCancer RegistryLinkage studiesRisk factorsBorderline associationElevated riskCancer diagnosisCancerEnvironmental exposuresWhite childrenCommon typeAir pollutionRisk
2020
Socioeconomic status and childhood central nervous system tumors in California
Francis SS, Wang R, Enders C, Prado I, Wiemels JL, Ma X, Metayer C. Socioeconomic status and childhood central nervous system tumors in California. Cancer Causes & Control 2020, 32: 27-39. PMID: 33113073, DOI: 10.1007/s10552-020-01348-3.Peer-Reviewed Original ResearchConceptsPrimary CNS tumorsCentral nervous system tumorsChildhood CNS tumorsCNS tumorsNervous system tumorsSocioeconomic statusSystem tumorsChildhood central nervous system tumorsCalifornia Cancer RegistryCalifornia birth recordsSubset of subjectsHigher socioeconomic statusCancer RegistryCancer mortalitySubgroup analysisRisk factorsChildhood cancerSubsequent riskEmbryonal tumorsParental socioeconomic statusInsurance utilizationBirth recordsTumorsMedian household incomeSpecific exposures
2017
Parental Age and Risk of Pediatric Cancer in the Offspring: A Population-Based Record-Linkage Study in California
Wang R, Metayer C, Morimoto L, Wiemels JL, Yang J, DeWan AT, Kang A, Ma X. Parental Age and Risk of Pediatric Cancer in the Offspring: A Population-Based Record-Linkage Study in California. American Journal Of Epidemiology 2017, 186: 843-856. PMID: 28535175, PMCID: PMC5860074, DOI: 10.1093/aje/kwx160.Peer-Reviewed Original ResearchConceptsRecord linkage studyMaternal ageOdds ratioPediatric cancerParental agePopulation-based record linkage studyCentral nervous system tumorsRisk of lymphomaPopulation-based studyCancer registry dataNervous system tumorsRisk of leukemiaAge group 0Ages 0Pediatric cancer riskOlder paternal ageOlder age groupsTypes of cancerSystem tumorsRegistry dataCancer riskHigh riskGroup 0Birth recordsAge groups
2016
Cesarean Section and Risk of Childhood Acute Lymphoblastic Leukemia in a Population-Based, Record-Linkage Study in California
Wang R, Wiemels JL, Metayer C, Morimoto L, Francis SS, Kadan-Lottick N, DeWan AT, Zhang Y, Ma X. Cesarean Section and Risk of Childhood Acute Lymphoblastic Leukemia in a Population-Based, Record-Linkage Study in California. American Journal Of Epidemiology 2016, 185: 96-105. PMID: 27986703, PMCID: PMC5253971, DOI: 10.1093/aje/kww153.Peer-Reviewed Original ResearchConceptsElective C-sectionAcute lymphoblastic leukemiaChildhood acute lymphoblastic leukemiaC-sectionCesarean sectionLymphoblastic leukemiaHigh riskPopulation-based case-control studyPeak ageEmergency C-sectionRecord linkage studyCancer registry dataCase-control studyPotential risk factorsEtiology of childhoodRelationship of modeVaginal deliveryRisk factorsRole of deliveryRegistry dataElevated riskBirth recordsInaccurate recallChildhoodRiskBirth weight and risk of paediatric Hodgkin lymphoma: Findings from a population-based record linkage study in California
Triebwasser C, Wang R, DeWan AT, Metayer C, Morimoto L, Wiemels JL, Kadan-Lottick N, Ma X. Birth weight and risk of paediatric Hodgkin lymphoma: Findings from a population-based record linkage study in California. European Journal Of Cancer 2016, 69: 19-27. PMID: 27814470, PMCID: PMC5125877, DOI: 10.1016/j.ejca.2016.09.016.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAge of OnsetBirth OrderBirth WeightCaliforniaCase-Control StudiesChildChild, PreschoolEthnicityFemaleFetal MacrosomiaHodgkin DiseaseHumansInfantInfant, Low Birth WeightInfant, NewbornInformation Storage and RetrievalLogistic ModelsMaleMaternal AgeOdds RatioPaternal AgeRisk FactorsConceptsAge of diagnosisPediatric Hodgkin lymphomaHigh birth weightBirth weightTime of deliveryHodgkin's lymphomaOdds ratioPopulation-based record linkage studyPopulation-based case-control studyBirth orderNormal birth weightRecord linkage studyCase-control studyConditional logistic regressionMagnitude of associationSubgroup of childrenPerinatal factorsMaternal ageEtiological investigationBirth recordsPaternal ageHL casesDisease riskLogistic regressionDiagnosisAir toxics and early childhood acute lymphocytic leukemia in Texas, a population based case control study
Symanski E, Tee Lewis PG, Chen TY, Chan W, Lai D, Ma X. Air toxics and early childhood acute lymphocytic leukemia in Texas, a population based case control study. Environmental Health 2016, 15: 70. PMID: 27301866, PMCID: PMC4908700, DOI: 10.1186/s12940-016-0154-8.Peer-Reviewed Original ResearchMeSH KeywordsAdultAir PollutantsBenzeneButadienesCase-Control StudiesChild, PreschoolEnvironmental MonitoringFemaleHumansInfantInfant, NewbornMaleMaternal ExposureOdds RatioPolycyclic Aromatic HydrocarbonsPrecursor Cell Lymphoblastic Leukemia-LymphomaPregnancyPrenatal Exposure Delayed EffectsTexasYoung AdultConceptsAcute lymphocytic leukemiaCo-pollutant modelsCase-control studySingle-pollutant modelsChildhood leukemiaLymphocytic leukemiaChildhood acute lymphocytic leukemiaBirth certificatesCancer registry casesPopulation-based controlsEarly life exposureMixed effects logistic regression modelsEarly childhood risksLogistic regression modelsPotential confoundersEtiologic roleLowest quartileRegistry casesInfant characteristicsLife exposurePediatric cancerMaternal addressControl studyBirth recordsLeukemia
2015
Birth weight, fetal growth, and risk of pediatric rhabdomyosarcoma: an updated record linkage study in California
Morimoto LM, McCauley K, Ma X, Wiemels JL, Chokkalingam AP, Metayer C. Birth weight, fetal growth, and risk of pediatric rhabdomyosarcoma: an updated record linkage study in California. Annals Of Epidemiology 2015, 26: 141-145. PMID: 26795698, DOI: 10.1016/j.annepidem.2015.11.007.Peer-Reviewed Original ResearchConceptsRisk of rhabdomyosarcomaHigh birth weightBirth weightGestational ageNon-Hispanic white childrenPost-term babiesCalifornia Cancer RegistryNormal gestational ageRecord linkage studyConditional logistic regressionCalifornia birth recordsNon-Hispanic whitesIndication of associationCancer RegistryBirth characteristicsFetal growthPediatric rhabdomyosarcomaRMS casesLower riskBirth recordsEthnic groupsLarger studyLogistic regressionWhite childrenAge
2005
Maternal Pregnancy Loss, Birth Characteristics, and Childhood Leukemia (United States)
Ma X, Metayer C, Does MB, Buffler PA. Maternal Pregnancy Loss, Birth Characteristics, and Childhood Leukemia (United States). Cancer Causes & Control 2005, 16: 1075-1083. PMID: 16184473, DOI: 10.1007/s10552-005-0356-9.Peer-Reviewed Original ResearchMeSH KeywordsAbortion, SpontaneousAdolescentBirth CertificatesBirth IntervalsBirth OrderBirth WeightCaliforniaCase-Control StudiesChildChild, PreschoolFemaleHumansInfantInfant, NewbornLeukemia, Myeloid, AcuteMalePrecursor Cell Lymphoblastic Leukemia-LymphomaPregnancyPregnancy, High-RiskRisk AssessmentRisk FactorsConceptsBirth characteristicsPregnancy lossChildhood leukemiaOdds ratioNorthern California Childhood Leukemia StudyHistory of miscarriageConfidence intervalsRisk of AMLConditional logistic regressionDetailed reproductive historyCalifornia Childhood Leukemia StudyChildhood Leukemia StudyChildhood AMLIncident casesBirth weightMaternal historyIndex childReproductive historyBirth recordsLogistic regressionRecall biasBirth certificatesLeukemia StudyAMLLeukemia
2004
Control Selection Strategies in Case-Control Studies of Childhood Diseases
Ma X, Buffler PA, Layefsky M, Does MB, Reynolds P. Control Selection Strategies in Case-Control Studies of Childhood Diseases. American Journal Of Epidemiology 2004, 159: 915-921. PMID: 15128601, DOI: 10.1093/aje/kwh136.Peer-Reviewed Original Research