Accelerated aging mediates the associations of unhealthy lifestyles with cardiovascular disease, cancer, and mortality
Li X, Cao X, Zhang J, Fu J, Mohedaner M, Danzengzhuoga, Sun X, Yang G, Yang Z, Kuo C, Chen X, Cohen A, Liu Z. Accelerated aging mediates the associations of unhealthy lifestyles with cardiovascular disease, cancer, and mortality. Journal Of The American Geriatrics Society 2023, 72: 181-193. PMID: 37789775, PMCID: PMC11078652, DOI: 10.1111/jgs.18611.Peer-Reviewed Original ResearchIncident cardiovascular diseaseCardiovascular diseaseUnhealthy lifestyleCause mortalityIncident cancerUK BiobankCox proportional hazards modelUnhealthy lifestyle scoreAssociation of lifestyleNutrition Examination SurveyUS National HealthProportional hazards modelAdverse health outcomesAge accelerationBiological age accelerationLifestyle interventionCVD mortalityLifestyle scoreExamination SurveyCancer mortalityBlood biomarkersMorbidity riskNational HealthMediation proportionHazards model