2011
Differential Features of Colorectal Cancer (CRC) in Patients With Probable Non-Sporadic Mismatch Repair Deficiency Without Germline Mutation
Soler M, Pérez-Carbonell L, Guarinos C, Ruiz-Ponte C, Brea A, Castillejo A, Barberá V, Sanchez-Fortun C, Sempere-Robles L, Bujanda L, Clofent J, Llor X, Andreu M, Castells A, Carracedo A, Soto J, Payá A, Alenda C, Jover R. Differential Features of Colorectal Cancer (CRC) in Patients With Probable Non-Sporadic Mismatch Repair Deficiency Without Germline Mutation. Gastroenterology 2011, 140: s-190-s-191. DOI: 10.1016/s0016-5085(11)60767-1.Peer-Reviewed Original Research
2010
S1994 Base Excision Repair Genes MYH, Ogg1 and Nudt1 and Mismatch Repair Gene Variants in Hereditary Non-Polyposis Colorectal Cancer Without Mismatch Repair Deficiency (MSS HNPCC)
Xicola R, Garre P, Doyle B, Bandipalliam P, Sapoznik V, Syngal S, Castells A, Jover R, Andreu M, Boland C, Goel A, Caldes T, Llor X. S1994 Base Excision Repair Genes MYH, Ogg1 and Nudt1 and Mismatch Repair Gene Variants in Hereditary Non-Polyposis Colorectal Cancer Without Mismatch Repair Deficiency (MSS HNPCC). Gastroenterology 2010, 138: s-297. DOI: 10.1016/s0016-5085(10)61365-0.Peer-Reviewed Original ResearchAberrant DNA Methylation in Hereditary Nonpolyposis Colorectal Cancer Without Mismatch Repair Deficiency
Goel A, Xicola RM, Nguyen T, Doyle BJ, Sohn VR, Bandipalliam P, Rozek LS, Reyes J, Cordero C, Balaguer F, Castells A, Jover R, Andreu M, Syngal S, Boland CR, Llor X. Aberrant DNA Methylation in Hereditary Nonpolyposis Colorectal Cancer Without Mismatch Repair Deficiency. Gastroenterology 2010, 138: 1854-1862.e1. PMID: 20102720, PMCID: PMC2859993, DOI: 10.1053/j.gastro.2010.01.035.Peer-Reviewed Original ResearchMeSH KeywordsAdaptor Proteins, Signal TransducingAdultAgedAged, 80 and overBase SequenceBasic Helix-Loop-Helix Transcription FactorsColorectal Neoplasms, Hereditary NonpolyposisCore Binding Factor Alpha 3 SubunitDNA MethylationDNA Mismatch RepairEpigenesis, GeneticFemaleGene Expression Regulation, NeoplasticGenetic Predisposition to DiseaseGenomic InstabilityHumansLong Interspersed Nucleotide ElementsMaleMicrosatellite RepeatsMiddle AgedMolecular Sequence DataMutationMutL Protein Homolog 1Nerve Tissue ProteinsNuclear ProteinsPedigreePhenotypeProto-Oncogene ProteinsProto-Oncogene Proteins B-rafProto-Oncogene Proteins p21(ras)Ras ProteinsSpainSuppressor of Cytokine Signaling 1 ProteinSuppressor of Cytokine Signaling ProteinsUnited StatesConceptsHereditary nonpolyposis colorectal cancerNonpolyposis colorectal cancerHNPCC tumorsMismatch repair deficiencyColorectal cancerMicrosatellite instabilityGermline mismatch repair (MMR) gene mutationsLynch syndrome cancersMismatch repair gene mutationsRepair deficiencyBest diagnostic approachBRAF mutation statusRepair gene mutationsSporadic microsatellite instabilityV600E BRAF mutationLINE-1 methylationSyndrome cancersAmsterdam criteriaLynch syndromeKRAS mutationsTreatment responseBRAF mutationsHigh indexTumor behaviorCarcinogenic pathways
2009
M1930 Identification of Genomic Variants in Hereditary Non-Polyposis Colorectal Cancer Without Mismatch Repair Deficiency (MSS HNPCC)
Xicola R, Caldes T, Garre P, Doyle B, Bandipalliam P, Syngal S, Grzybowski J, Sapoznik V, Grzybowski M, Martinez T, Murugappan S, Castells A, Jover R, Andreu M, Goel A, Llor X. M1930 Identification of Genomic Variants in Hereditary Non-Polyposis Colorectal Cancer Without Mismatch Repair Deficiency (MSS HNPCC). Gastroenterology 2009, 136: a-449. DOI: 10.1016/s0016-5085(09)62065-5.Peer-Reviewed Original Research198 CpG-Island Methylator Phenotype (CIMP) and Alterations in RAS-Raf Signaling in Hereditary Non-Polyposis Colorectal Cancers Without Mismatch Repair Deficiency (MSS HNPCC)
Xicola R, Nguyen T, Doyle B, Bandipalliam P, Syngal S, Reyes J, Cordero C, Grzybowski J, Sapoznik V, Grzybowski M, Castells A, Jover R, Andreu M, Boland C, Llor X, Goel A. 198 CpG-Island Methylator Phenotype (CIMP) and Alterations in RAS-Raf Signaling in Hereditary Non-Polyposis Colorectal Cancers Without Mismatch Repair Deficiency (MSS HNPCC). Gastroenterology 2009, 136: a-37. DOI: 10.1016/s0016-5085(09)60169-4.Peer-Reviewed Original Research