Enrichment of inflammatory bowel disease and colorectal cancer risk variants in colon expression quantitative trait loci
Hulur I, Gamazon ER, Skol AD, Xicola RM, Llor X, Onel K, Ellis NA, Kupfer SS. Enrichment of inflammatory bowel disease and colorectal cancer risk variants in colon expression quantitative trait loci. BMC Genomics 2015, 16: 138. PMID: 25766683, PMCID: PMC4351699, DOI: 10.1186/s12864-015-1292-z.Peer-Reviewed Original ResearchConceptsInflammatory bowel diseaseColorectal cancerBowel diseaseSingle nucleotide polymorphismsBody mass indexType 2 diabetesHealthy African AmericansColorectal cancer risk variantsMass indexTarget genesColonic diseaseColonic samplesDiseaseNovel target geneBackgroundGenome-wide association studiesHuman colonDifferent ethnic groupsRisk variantsAfrican AmericansColonFalse discovery rateGenetic variantsNucleotide polymorphismsBiological differencesFunctional role