Dynamic instability of clathrin assembly provides proofreading control for endocytosis
Chen Y, Yong J, Martínez-Sánchez A, Yang Y, Wu Y, De Camilli P, Fernández-Busnadiego R, Wu M. Dynamic instability of clathrin assembly provides proofreading control for endocytosis. Journal Of Cell Biology 2019, 218: 3200-3211. PMID: 31451612, PMCID: PMC6781453, DOI: 10.1083/jcb.201804136.Peer-Reviewed Original ResearchConceptsClathrin-coated pitsCell-free reconstitution systemClathrin coat formationSingle-molecule imagingAssembly machineryCargo sortingATPase Hsc70Hsc70 functionClathrin assemblyCoat formationCargo incorporationReconstitution systemDynamic exchangeProofreading mechanismClathrinEndocytosisAssembly rateCargoCheckpoint