2000
Vasomotor control in arterioles of the mouse cremaster muscle
HUNGERFORD J, SESSA W, SEGAL S. Vasomotor control in arterioles of the mouse cremaster muscle. The FASEB Journal 2000, 14: 197-207. PMID: 10627294, DOI: 10.1096/fasebj.14.1.197.Peer-Reviewed Original ResearchConceptsMouse cremaster muscleVasomotor controlCremaster musclePerivascular sympathetic nerve stimulationAnesthetized C57Bl6 miceMicroiontophoresis of acetylcholineSympathetic nerve stimulationNitro-L-arginineConcentration-dependent vasoconstrictionBlood flow controlCremaster muscle preparationFocal vasoconstrictionVasodilatory responseNerve stimulationTransgenic mouse technologyVasomotor responsesC57BL6 miceCardiovascular functionNormal miceMuscle preparationsArteriolesBiphasic responseIntravital microscopyAcetylcholineVasoconstriction
1999
NO overproduction by eNOS precedes hyperdynamic splanchnic circulation in portal hypertensive rats
Wiest R, Shah V, Sessa W, Groszmann R. NO overproduction by eNOS precedes hyperdynamic splanchnic circulation in portal hypertensive rats. American Journal Of Physiology 1999, 276: g1043-g1051. PMID: 10198349, DOI: 10.1152/ajpgi.1999.276.4.g1043.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBlood Flow VelocityBlood PressureEndothelium, VascularHypertension, PortalKineticsLuminescent MeasurementsMaleMesenteric Artery, SuperiorMethoxamineNitric OxideNitric Oxide SynthaseNitric Oxide Synthase Type IIINitroarginineRatsRats, Sprague-DawleySplanchnic CirculationStress, MechanicalConceptsHyperdynamic splanchnic circulationSuperior mesenteric arterySplanchnic circulationSham ratsNitric oxide synthase upregulationHyperdynamic circulatory syndromeNO metabolites concentrationPortal hypertensive ratsENOS protein levelsHigh blood flowSignificant hyporesponsivenessArterial vasodilatationL-NNAPortal hypertensionPVL ratsAgonist methoxamineCirculatory syndromeENOS upregulationHypertensive ratsMesenteric arteryNomega-nitroNO inhibitorBlood flowDay 3L-arginine