2016
Gender is a determinative factor in the initial clinical presentation of eosinophilic esophagitis
Lynch K, Dhalla S, Chedid V, Ravich W, Stein E, Montgomery E, Bochner B, Clarke J. Gender is a determinative factor in the initial clinical presentation of eosinophilic esophagitis. Diseases Of The Esophagus 2016, 29: 174-178. PMID: 25626069, DOI: 10.1111/dote.12307.Peer-Reviewed Original ResearchConceptsInitial clinical presentationEndoscopic findingsClinical presentationChest painFood impactionEosinophilic esophagitisElectronic medical record databaseTime of diagnosisImmune-mediated diseasesMedical record databaseT-testChi-squared analysisStudent's t-testEoE populationEoE patientsEsophageal dysfunctionEndoscopy findingsEsophageal dysmotilityPatient demographicsEsophageal perforationInflammatory symptomsAtypical symptomsConsensus guidelinesClinical differencesInclusion criteria
1996
Botulinum toxin for achalasia: Long-term outcome and predictors of response
Pasricha P, Rai R, Ravich W, Hendrix T, Kalloo A. Botulinum toxin for achalasia: Long-term outcome and predictors of response. Gastroenterology 1996, 110: 1410-1415. PMID: 8613045, DOI: 10.1053/gast.1996.v110.pm8613045.Peer-Reviewed Original ResearchConceptsLong-term outcomesPredictors of responseMedian durationBotulinum toxinType of achalasiaThird of patientsMajority of patientsDuration of illnessDuration of responseLower esophageal sphincterEffective short-term reliefYears of ageShort-term reliefPrevious dilationLatter patientsToxin injectionVigorous achalasiaEsophageal sphincterRadiological characteristicsEffective treatmentAchalasiaPatientsSecond injectionResponse rateNineteen responders
1995
Intrasphincteric Botulinum Toxin for the Treatment of Achalasia
Pasricha P, Ravich W, Hendrix T, Sostre S, Jones B, Kalloo A. Intrasphincteric Botulinum Toxin for the Treatment of Achalasia. New England Journal Of Medicine 1995, 332: 774-778. PMID: 7862180, DOI: 10.1056/nejm199503233321203.Peer-Reviewed Original ResearchConceptsLower esophageal sphincterEsophageal sphincterBotulinum toxinPlacebo groupMean decreaseSymptom scoresTreatment groupsMean increaseDisorders of swallowingIntrasphincteric botulinum toxinDouble-blind trialTreatment of achalasiaMonths 14 patientsSerious adverse effectsSymptomatic improvementEsophageal retentionParalytic agentsScintigraphic studiesEsophageal scintigraphySphincterAchalasiaPatientsAdverse effectsPlaceboMonths
1994
Treatment of achalasia with intrasphincteric injection of botulinum toxin. A pilot trial.
Pasricha P, Ravich W, Hendrix T, Sostre S, Jones B, Kalloo A. Treatment of achalasia with intrasphincteric injection of botulinum toxin. A pilot trial. Annals Of Internal Medicine 1994, 121: 590-1. PMID: 8085691, DOI: 10.7326/0003-4819-121-8-199410150-00006.Peer-Reviewed Original Research
1993
Effects of intrasphincteric botulinum toxin on the lower esophageal sphincter in piglets
Pasricha P, Ravich W, Kalloo A. Effects of intrasphincteric botulinum toxin on the lower esophageal sphincter in piglets. Gastroenterology 1993, 105: 1045-1049. PMID: 8405847, DOI: 10.1016/0016-5085(93)90947-b.Peer-Reviewed Original ResearchConceptsLES pressureLower esophageal sphincter pressureIntrasphincteric botulinum toxinEsophageal sphincter pressureLower esophageal sphincterRelease of acetylcholineGastrointestinal smooth muscleNormal saline injectionEvidence of toxicityBaseline lower esophageal sphincter pressureBoTx injectionNoncholinergic pathwaysAnticholinergic effectsSphincter pressureLES toneEsophageal sphincterGastrointestinal sphinctersBotulinum toxinNormal salineSaline injectionNerve terminalsParadoxical responseSmooth muscleBoTxSkeletal muscle
1992
Swallowing dysfunction in the postpolio syndrome: a cinefluorographic study.
Jones B, Buchholz D, Ravich W, Donner M. Swallowing dysfunction in the postpolio syndrome: a cinefluorographic study. American Journal Of Roentgenology 1992, 158: 283-6. PMID: 1729782, DOI: 10.2214/ajr.158.2.1729782.Peer-Reviewed Original ResearchConceptsStructural lesionsConstrictor musclePoor laryngeal elevationPrevertebral soft tissueSeverity of decompensationPharyngeal constrictor muscleInferior constrictor muscleCricopharyngeal levelFocal strictureBilateral weaknessProgressive dysphagiaLaryngeal penetrationPostpolio syndromeCricopharyngeus muscleDistal esophagusLaryngeal elevationPostpolio patientsLaryngeal closureLuminal narrowingCervical esophagusZenker's diverticulumRadiographic abnormalitiesRemote historyEpiglottic tiltSoft palateCaustic ingestion injuries of the upper aerodigestive tract
Scott J, Jones B, Eisele D, Ravich W. Caustic ingestion injuries of the upper aerodigestive tract. The Laryngoscope 1992, 102: 1-8. PMID: 1731151, DOI: 10.1288/00005537-199201000-00001.Peer-Reviewed Original ResearchConceptsCaustic ingestionJohns Hopkins Swallowing CenterCaustic ingestion injuryDynamic radiographic studiesUpper aerodigestive tractLaryngeal protectionNasopharyngeal regurgitationIngestion injuryCaustic injuryRoentgenographic findingsAerodigestive tractMuscle dysfunctionEsophageal stenosisSwallowing centerHypopharyngeal stenosisFunctional abnormalitiesRadiographic studiesOral cavityRadiographic analysisInjuryPatientsMultidisciplinary approachStenosisIngestionSuch cases
1991
Gastric antral vascular ectasia ("watermelon stomach"): radiologic findings.
Urban B, Jones B, Fishman E, Kern S, Ravich W. Gastric antral vascular ectasia ("watermelon stomach"): radiologic findings. Radiology 1991, 178: 517-8. PMID: 1987618, DOI: 10.1148/radiology.178.2.1987618.Peer-Reviewed Original Research
1990
Esophageal motility in an adult with a congenital H-type tracheoesophageal fistula
Heitmiller R, Nikoomanesh P, Ravich W. Esophageal motility in an adult with a congenital H-type tracheoesophageal fistula. Dysphagia 1990, 5: 138-141. PMID: 2249489, DOI: 10.1007/bf02412636.Peer-Reviewed Original ResearchConceptsCongenital H-type tracheoesophageal fistulaH-type tracheoesophageal fistulaTracheoesophageal fistulaRespiratory symptomsNormal lower esophageal sphincter pressureLower esophageal sphincter pressureLow-amplitude peristalsisCommon presenting complaintEsophageal motor abnormalitiesEsophageal sphincter pressureCongenital tracheoesophageal fistulaEsophageal symptomsSphincter pressureAdult patientsPresenting complaintEsophageal motilityMotor abnormalitiesFistula repairFistulaPatientsSymptomsFindings persistCase historiesAbnormalitiesPeristalsis
1989
Psychogenic dysphagia and globus: Reevaluation of 23 patients
Ravich W, Wilson R, Jones B, Donner M. Psychogenic dysphagia and globus: Reevaluation of 23 patients. Dysphagia 1989, 4: 35-38. PMID: 2640174, DOI: 10.1007/bf02407400.Peer-Reviewed Original ResearchConceptsPsychogenic dysphagiaPsychogenic originJohns Hopkins Swallowing CenterCause of dysphagiaProgression of symptomsAttribution of symptomsResults of reevaluationGlobus sensationGlobus hystericusMotor dysfunctionEsophageal pathologySwallowing centerSwallowing disordersStructural lesionsPharyngeal diseaseDysphagiaPatientsReferral recordsCenter evaluationSymptomsDiagnosisThorough evaluationCausePsychological causesDysfunction
1987
Granular small bowel mucosa: A reflection of villous abnormality
Jones B, Hamilton S, Rubesin S, Bayless T, Ravich W, Hendrix T. Granular small bowel mucosa: A reflection of villous abnormality. Gastrointestinal Radiology 1987, 12: 219-225. PMID: 3596139, DOI: 10.1007/bf01885147.Peer-Reviewed Original ResearchConceptsCrohn's diseaseHistopathologic examinationExtensive small bowel resectionSmall bowel Crohn's diseaseEarly inflammatory diseaseProtein-losing enteropathySmall bowel ischemiaSmall bowel resectionMucosal granularityPancreatic glucagonomaBowel ischemiaRadiation enteritisBowel resectionGranular mucosaNonspecific findingsSmall bowelVillous hypertrophyIntestinal adaptationInflammatory diseasesVillous abnormalitiesRadiographic appearanceVillous morphologyVillous enlargementVillous structureDiseasePharyngeal findings in 21 patients with achalasia of the esophagus
Jones B, Donner M, Rubesin S, Ravich W, Hendrix T. Pharyngeal findings in 21 patients with achalasia of the esophagus. Dysphagia 1987, 2: 87-92. PMID: 3507299, DOI: 10.1007/bf02408139.Peer-Reviewed Original ResearchCongenital laryngotracheal (LT) cleft: Report of a successful repair in an adult
Kashima H, Marsh B, Donner M, Ravich W, Robertson D. Congenital laryngotracheal (LT) cleft: Report of a successful repair in an adult. Dysphagia 1987, 2: 18-24. PMID: 3507286, DOI: 10.1007/bf02406973.Peer-Reviewed Original Research
1985
The swallowing center: Concepts and procedures
Ravich W, Donner M, Kashima H, Buchholz D, Marsh B, Hendrix T, Kramer S, Jones B, Bosma J, Siebens A, Linden P. The swallowing center: Concepts and procedures. Gastrointestinal Radiology 1985, 10: 255-261. PMID: 4029542, DOI: 10.1007/bf01893109.Peer-Reviewed Original Research
1984
Adenocarcinoma in Barrett's esophagus after elimination of gastroesophageal reflux
Hamilton S, Hutcheon D, Ravich W, Cameron J, Paulson M. Adenocarcinoma in Barrett's esophagus after elimination of gastroesophageal reflux. Gastroenterology 1984, 86: 356-360. PMID: 6690363, DOI: 10.1016/0016-5085(84)90423-2.Peer-Reviewed Original ResearchConceptsBarrett's esophagusGastroesophageal refluxColonic interpositionBarrett's mucosaAbsence of refluxSevere reflux esophagitisDevelopment of adenocarcinomaLong-term surveillanceLower esophageal strictureAntireflux therapyReflux esophagitisSubtotal resectionEsophageal strictureRadiographic findingsInterposition proceduresEsophagusAdenocarcinomaMucosaRefluxPatientsInterpositionProbe recordingsEsophagectomyEsophagitisResection
1983
Fructose: Incomplete Intestinal Absorption in Humans
Ravich W, Bayless T, Thomas M. Fructose: Incomplete Intestinal Absorption in Humans. Gastroenterology 1983, 84: 26-29. PMID: 6847852, DOI: 10.1016/s0016-5085(83)80162-0.Peer-Reviewed Original ResearchConceptsIncomplete absorptionIncomplete intestinal absorptionIngestion of sucroseBreath hydrogen analysisAbdominal symptomsGastrointestinal symptomsFructose absorptionHealthy volunteersIntestinal absorptionBreath hydrogenSmall intestinePeak riseSymptomsSugar loadSubjectsCrampsDiarrheaPatientsIngestionIntestineVolunteers