Innate type 2 immunity controls hair follicle commensalism by Demodex mites
Ricardo-Gonzalez R, Kotas M, O’Leary C, Tenvooren I, Marquez D, Singh K, Damsky W, Liao C, Schroeder A, Cohen J, Fassett M, Lee J, Daniel S, Bittinger K, Diaz R, Fraser J, Ansel K, Spitzer M, Liang H, Locksley R. Innate type 2 immunity controls hair follicle commensalism by Demodex mites. The Journal Of Immunology 2022, 208: 50.39-50.39. DOI: 10.4049/jimmunol.208.supp.50.39.Peer-Reviewed Original ResearchIL-13Hair folliclesDemodex mitesEpithelial hair follicleType 2 cytokinesCalifornia San FranciscoAdaptive immune systemEpithelial cell proliferationImmune checkpointsImmune dysfunctionAcne rosaceaInflammatory cellsIL-4Inflammatory conditionsRobert Wood Johnson FoundationInflammatory programHigh burdenEpithelial proliferationIL-4RACutaneous integrityImmune systemCommensal parasitesAnagen onsetBarrier functionCell proliferation