2023
Cystic Kidney Diseases in Children and Adults: Differences and Gaps in Clinical Management
Hanna C, Iliuta I, Besse W, Mekahli D, Chebib F. Cystic Kidney Diseases in Children and Adults: Differences and Gaps in Clinical Management. Seminars In Nephrology 2023, 43: 151434. PMID: 37996359, DOI: 10.1016/j.semnephrol.2023.151434.Peer-Reviewed Original ResearchConceptsCystic kidney diseaseKidney diseaseAutosomal dominant polycystic kidney diseaseAutosomal-dominant polycystic kidney diseasePolycystic kidney diseaseClinical managementDifferential diagnosisProgressive autosomal dominant polycystic kidney diseaseWide differential diagnosisKidney cystsV2 receptor antagonistKidney cystic diseaseDiagnosis of inherited disordersNext-generation sequencingRadiologic characteristicsKidney functionExtrarenal manifestationsFuture pregnanciesUnderlying conditionCystic diseaseLikely diagnosisFamily historyExtrarenal featuresPediatric diagnosesRecurrence risk
2007
Altered Natural Killer Cells in Type 1 Diabetic Patients
Rodacki M, Svoren B, Butty V, Besse W, Laffel L, Benoist C, Mathis D. Altered Natural Killer Cells in Type 1 Diabetic Patients. Diabetes 2007, 56: 177-185. PMID: 17192480, DOI: 10.2337/db06-0493.Peer-Reviewed Original ResearchConceptsType 1 diabetesBlood NK cellsType 1 diabetic patientsNK cellsNatural killer cellsDiabetic patientsNatural killerControl subjectsReduced activity of NK cellsKiller cellsDecreased expression of NKG2DActivity of NK cellsPatients relative to control subjectsDevelopment of type 1 diabetesHuman type 1 diabetesEarly onset of diabetesExpression of NKG2DType 1 diabetes pathogenesisGamma interferon expressionDuration of diseaseKIR gene haplotypesOnset of diabetesKIR2DS3 geneNOD miceGamma interferon