Calreticulin (CALR) mutation in myeloproliferative neoplasms (MPNs)
Luo W, Yu Z. Calreticulin (CALR) mutation in myeloproliferative neoplasms (MPNs). Stem Cell Investigation 2015, 2: 16. PMID: 27358884, PMCID: PMC4923638, DOI: 10.3978/j.issn.2306-9759.2015.08.01.Peer-Reviewed Original ResearchMyeloproliferative neoplasmsClinical presentationCALR mutationsClinical-molecular correlationsGene mutationsOptimal treatment strategyProtean clinical presentationsRisk of thrombosisHigher platelet countsCalreticulin mutationsCases of MPNCertain hematological parametersBetter prognosisPlatelet countTreatment strategiesHematological parametersMolecular alterationsMPL mutationsConventional morphological classificationHeterogeneous groupChromosomal alterationsPrognosisNeoplasmsCALRMolecular mechanisms