2001
Water Penetration and Binding to Ferric Myoglobin †
Cao W, Christian J, Champion P, Rosca F, Sage J. Water Penetration and Binding to Ferric Myoglobin †. Biochemistry 2001, 40: 5728-5737. PMID: 11341838, DOI: 10.1021/bi010067e.Peer-Reviewed Original ResearchConceptsH2O bindingHeme pocketHydrogen bondsHis-64Heme ironFlash photolysis investigationsPhotodissociation of NOFerric heme proteinsH2O ligandsWater moleculesNO photolysisHorse heart metmyoglobinHeme proteinsCO escapeBound waterRebinding rateSmall moleculesH2OPhotolysisDissociation constantBondsHydrogenHemeMoleculesPhysiological NO concentrations
2000
Femtosecond Multicolor Pump−Probe Spectroscopy of Ferrous Cytochrome c †
Wang W, Ye X, Demidov A, Rosca F, Sjodin T, Cao W, Sheeran M, Champion P. Femtosecond Multicolor Pump−Probe Spectroscopy of Ferrous Cytochrome c †. The Journal Of Physical Chemistry B 2000, 104: 10789-10801. DOI: 10.1021/jp0008602.Peer-Reviewed Original ResearchFemtosecond coherence spectroscopyLigand photolysisQuantum yieldAbsorption spectraTransient absorption spectraFerrous cytochrome cHigh quantum yieldUltrafast laser spectroscopyTi:sapphire laserInduce coherent oscillationsLigand recombinationMethionine ligandGeminate rebindingPhotolysis timeQ-bandCm-1Pulsed photoexcitationVibrational modesStructural relaxationCoherence spectroscopyHeme ironMP-8PhotolysisCoherent oscillationsLaser spectroscopy