2024
Hematuria Cancer Risk Score with Ultrasound Informs Cystoscopy Use in Patients with Hematuria
Tan W, Ahmad A, Zhou Y, Nathan A, Ogunbo A, Gbolahan O, Kallam N, Smith R, Khalifeh M, Tan W, Cohen D, Volanis D, Walter F, Sasieni P, Kamat A, Kelly J. Hematuria Cancer Risk Score with Ultrasound Informs Cystoscopy Use in Patients with Hematuria. European Urology Oncology 2024 PMID: 38811250, DOI: 10.1016/j.euo.2024.05.005.Peer-Reviewed Original ResearchCancer risk scoreRenal bladder ultrasoundTa bladder cancerUrinary tract cancerRisk scoreValidation cohortBladder cancerHealth care cost savingsBladder ultrasoundDiagnosis of urinary tract cancerInvasive proceduresDevelopment cohortIdentification of cancerSuspicion of bladder cancerSecondary careIndependent validation cohortReceiver operating characteristic curveUK hospitalsArea under the receiver operating characteristic curveOutcome measuresTriage of patientsConsecutive patientsPatient cohortCystoscopyHematuria
2021
Defining Factors Associated with High-quality Surgery Following Radical Cystectomy: Analysis of the British Association of Urological Surgeons Cystectomy Audit
Tan W, Leow J, Marchese M, Sridhar A, Hellawell G, Mossanen M, Teoh J, Fowler S, Colquhoun A, Cresswell J, Catto J, Trinh Q, Kelly J, Section of Oncology O. Defining Factors Associated with High-quality Surgery Following Radical Cystectomy: Analysis of the British Association of Urological Surgeons Cystectomy Audit. European Urology Open Science 2021, 33: 1-10. PMID: 34723215, PMCID: PMC8546928, DOI: 10.1016/j.euros.2021.08.005.Peer-Reviewed Original ResearchMixed-effects logistic regression modelsIndex admission mortalityLogistic regression modelsHigh-quality surgeryAdmission mortalityHierarchical mixed-effects logistic regression modelsSurgeon operative volumeBritish Association of Urological SurgeonsRadical cystectomyDelivery of careRegression modelsMedian surgeonHospital operative volumeEvaluate healthcareAnnual operative volumeOperative volumePatients treated with surgical excisionComplex oncologyUK hospitalsAssociated with high morbidityOutcome measuresHospital volumeMinimally invasive approachQuality assurance programmeMinimally invasive RC
2018
Radiofrequency-induced Thermo-chemotherapy Effect Versus a Second Course of Bacillus Calmette-Guérin or Institutional Standard in Patients with Recurrence of Non–muscle-invasive Bladder Cancer Following Induction or Maintenance Bacillus Calmette-Guérin Therapy (HYMN): A Phase III, Open-label, Randomised Controlled Trial
Tan W, Panchal A, Buckley L, Devall A, Loubière L, Pope A, Feneley M, Cresswell J, Issa R, Mostafid H, Madaan S, Bhatt R, McGrath J, Sangar V, Griffiths T, Page T, Hodgson D, Datta S, Billingham L, Kelly J. Radiofrequency-induced Thermo-chemotherapy Effect Versus a Second Course of Bacillus Calmette-Guérin or Institutional Standard in Patients with Recurrence of Non–muscle-invasive Bladder Cancer Following Induction or Maintenance Bacillus Calmette-Guérin Therapy (HYMN): A Phase III, Open-label, Randomised Controlled Trial. European Urology 2018, 75: 63-71. PMID: 30274699, DOI: 10.1016/j.eururo.2018.09.005.Peer-Reviewed Original ResearchConceptsNon-muscle-invasive bladder cancerDisease-free survival timeCarcinoma in situBacillus Calmette-GuerinSecond-line therapyTreatment armsComplete responseOpen-labelNo significant differenceBladder cancerCourse of bacillus Calmette-GuerinNon-muscle-invasive bladder cancer patientsBacillus Calmette-Guerin failuresCarcinoma in situ patientsStandard second-line therapyBacillus Calmette-Guerin therapyRecurrence of non-muscle-invasive bladder cancerStandard of care treatmentControlled trialsPapillary bladder lesionsPhase III randomised controlled trialMedian follow-upBladder cancer outcomesSignificant differenceOutcome measures