2024
Comparison between high-flow nasal cannula and conventional oxygen therapy in COVID-19 patients: a systematic review and meta-analysis
Wang J, Peng Y, Dai B, Hou H, Zhao H, Wang W, Tan W. Comparison between high-flow nasal cannula and conventional oxygen therapy in COVID-19 patients: a systematic review and meta-analysis. Therapeutic Advances In Respiratory Disease 2024, 18: 17534666231225323. PMID: 38230522, PMCID: PMC10798115, DOI: 10.1177/17534666231225323.Peer-Reviewed Original ResearchConceptsAcute hypoxemic respiratory failureHigh-flow nasal cannulaConventional oxygen therapyCOVID-19-related acute hypoxemic respiratory failureIntensive care unitHospital length of stayInvasive mechanical ventilationLength of stayIntensive care unit settingCOVID-19 patientsIntubation rateNasal cannulaMechanical ventilationOxygen therapyRatio of arterial oxygen partial pressure to fractional inspired oxygenHospital lengthArterial oxygen partial pressure to fractional inspired oxygenEfficacy of high-flow nasal cannulaIntensive care unit length of stayControlled trialsSystematic reviewRespiratory support strategiesIntensive care unit lengthHypoxemic respiratory failureMortality rate
2023
The effects of flow settings during high-flow nasal cannula support for adult subjects: a systematic review
Li J, Albuainain F, Tan W, Scott J, Roca O, Mauri T. The effects of flow settings during high-flow nasal cannula support for adult subjects: a systematic review. Critical Care 2023, 27: 78. PMID: 36855198, PMCID: PMC9974062, DOI: 10.1186/s13054-023-04361-5.Peer-Reviewed Original ResearchConceptsHigh-flow nasal cannulaHigh-flow nasal cannula treatmentIn vivo studiesPatient's peak inspiratory flowHigh-flow nasal cannula supportFraction of inspired oxygenPositive end-expiratory pressurePeak inspiratory flowSystematic reviewEnd-expiratory pressureDead space washoutNon-dependent lung regionsIn vitro studiesRisk of biasROX indexNasal cannulaClinical findingsImprove oxygenationPediatric populationPatient discomfortAlveolar overdistentionInspiratory flowWeb of SciencePatient comfortPatients
2022
Comparison between high-flow nasal cannula and noninvasive ventilation in COVID-19 patients: a systematic review and meta-analysis
Peng Y, Dai B, Zhao H, Wang W, Kang J, Hou H, Tan W. Comparison between high-flow nasal cannula and noninvasive ventilation in COVID-19 patients: a systematic review and meta-analysis. Therapeutic Advances In Respiratory Disease 2022, 16: 17534666221113663. PMID: 35861299, PMCID: PMC9340323, DOI: 10.1177/17534666221113663.Peer-Reviewed Original ResearchConceptsHigh-flow nasal cannulaAcute hypoxemic respiratory failureHigh-flow nasal cannula groupIntensive care unitClinical outcomes of COVID-19Noninvasive ventilation groupNoninvasive ventilationInvasive mechanical ventilationRandomized controlled trialsOutcomes of COVID-19Intubation rateNasal cannulaClinical outcomesCOVID-19-related acute hypoxemic respiratory failureMechanical ventilationHospital LOSPositive airway pressureHypoxemic respiratory failureMortality rateIntensive care unit LOSMeta-analysisSystematic reviewCPAP groupCOVID-19 patientsAirway pressureEffectiveness of the use of a high-flow nasal cannula to treat COVID-19 patients and risk factors for failure: a meta-analysis
Xu D, Dai B, Tan W, Zhao H, Wang W, Kang J. Effectiveness of the use of a high-flow nasal cannula to treat COVID-19 patients and risk factors for failure: a meta-analysis. Therapeutic Advances In Respiratory Disease 2022, 16: 17534666221091931. PMID: 35467449, PMCID: PMC9047804, DOI: 10.1177/17534666221091931.Peer-Reviewed Original ResearchConceptsHigh-flow nasal cannulaInitiation of high-flow nasal cannulaHigh-flow nasal cannula failureSequential Organ Failure AssessmentRegister of Randomized Controlled TrialsCOVID-19 patientsBody mass indexFailure groupROX indexRisk factorsHigher heart rateWhite blood cellsNasal cannulaChronic Health Evaluation (APACHE) II scoreEfficacy of high-flow nasal cannulaHeart rateDuration of HFNCOdds ratioCochrane Central Register of Randomized Controlled TrialsRisk of HFNC failureHigher white blood cellWhite blood cell countLower ROX indexOrgan Failure AssessmentPooled odds ratio
2019
Factors affecting FiO2 and PEEP during high‐flow nasal cannula oxygen therapy: A bench study
Sun Y, Dai B, Peng Y, Tan W, Zhao H. Factors affecting FiO2 and PEEP during high‐flow nasal cannula oxygen therapy: A bench study. The Clinical Respiratory Journal 2019, 13: 758-764. PMID: 31465634, DOI: 10.1111/crj.13087.Peer-Reviewed Original ResearchConceptsHigh-flow nasal cannulaPositive end-expiratory pressurePeak inspiratory flowHigh-flow nasal cannula oxygen therapyOxygen therapyTidal volumeInspiratory flowFraction of inspired O<sub>2</sub> (FiO<sub>2</sub>Nasal cannula oxygen therapyTherapy in vitroEnd-expiratory pressureNasal cannulaMultivariate linear regressionConsecutive breathsTherapyBench studySet-flow