Effectiveness of the use of a high-flow nasal cannula to treat COVID-19 patients and risk factors for failure: a meta-analysis
Xu D, Dai B, Tan W, Zhao H, Wang W, Kang J. Effectiveness of the use of a high-flow nasal cannula to treat COVID-19 patients and risk factors for failure: a meta-analysis. Therapeutic Advances In Respiratory Disease 2022, 16: 17534666221091931. PMID: 35467449, PMCID: PMC9047804, DOI: 10.1177/17534666221091931.Peer-Reviewed Original ResearchConceptsHigh-flow nasal cannulaInitiation of high-flow nasal cannulaHigh-flow nasal cannula failureSequential Organ Failure AssessmentRegister of Randomized Controlled TrialsCOVID-19 patientsBody mass indexFailure groupROX indexRisk factorsHigher heart rateWhite blood cellsNasal cannulaChronic Health Evaluation (APACHE) II scoreEfficacy of high-flow nasal cannulaHeart rateDuration of HFNCOdds ratioCochrane Central Register of Randomized Controlled TrialsRisk of HFNC failureHigher white blood cellWhite blood cell countLower ROX indexOrgan Failure AssessmentPooled odds ratio