2023
Anti-σ28 Factor FlgM Regulates Flagellin Gene Expression and Flagellar Polarity of Treponema denticola
Kurniyati K, Chang Y, Guo W, Liu J, Malkowski M, Li C. Anti-σ28 Factor FlgM Regulates Flagellin Gene Expression and Flagellar Polarity of Treponema denticola. Journal Of Bacteriology 2023, 205: e00463-22. PMID: 36715541, PMCID: PMC9945498, DOI: 10.1128/jb.00463-22.Peer-Reviewed Original ResearchConceptsFlagellin gene expressionPeriplasmic flagellaGene expressionSpirochete Treponema denticolaOral spirochete Treponema denticolaCryo-electron tomography analysisFlagellar gene expressionCore RNA polymeraseGroup of bacteriaFlgM proteinFlagellar genesBipolar flagellaHeterologous expressionDependent promotersFlagellar numberRNA polymeraseFlgMFliAMutational analysisFlagellin geneMolecular mechanismsSpirochete motilityHuman diseasesLines of evidenceEnds of cells
2020
The flagellar motor of Vibrio alginolyticus undergoes major structural remodeling during rotational switching
Carroll BL, Nishikino T, Guo W, Zhu S, Kojima S, Homma M, Liu J. The flagellar motor of Vibrio alginolyticus undergoes major structural remodeling during rotational switching. ELife 2020, 9: e61446. PMID: 32893817, PMCID: PMC7505661, DOI: 10.7554/elife.61446.Peer-Reviewed Original ResearchConceptsFlagellar motorRotational switchingBacterial flagellar motorLarge conformational rearrangementsCryo-electron tomographyMajor structural remodelingConformational remodelingRotor complexCytoplasmic ringConformational rearrangementsProtein compositionConformational changesC-ringNovel insightsFliNFlagellaMolecular architectureFLIMVibrioFliGRemodelingMutantsStructural remodelingMechanismCells