2024
Associations Between Neighborhood Resources and Youth’s Response to Reward Omission in a Task Modeling Negatively Biased Environments
Brown B, Nguyen L, Morales I, Cardinale E, Tseng W, McKay C, Kircanski K, Brotman M, Pine D, Leibenluft E, Linke J. Associations Between Neighborhood Resources and Youth’s Response to Reward Omission in a Task Modeling Negatively Biased Environments. Journal Of The American Academy Of Child & Adolescent Psychiatry 2024 PMID: 38763411, DOI: 10.1016/j.jaac.2024.05.011.Peer-Reviewed Original ResearchChildhood Opportunity IndexPaper self-identifiesNeighborhood resourcesAbstractText Label="DIVERSITY &Functional magnetic resonance imagingAbstractText Label="METHOD" NlmCategory="METHODS">Ethnic groupsReward omissionBlocked goalsNeurobiological levelMood disordersNeurodevelopmental trajectoriesLocal processing modeMental healthReduced connectivityDiverse sampleInvestigate associationsControl networkNeighborhood featuresQuantify accessProvincial hubsPromote sexRewardOpportunity IndexMagnetic resonance imagingAssociations between trauma exposure and irritability within the family unit: a network approach
Cotter G, Morreale K, Valdegas A, Fish M, Beebe R, Grasso D, Stover C, Tseng W. Associations between trauma exposure and irritability within the family unit: a network approach. Journal Of Child Psychology And Psychiatry 2024 PMID: 38710637, DOI: 10.1111/jcpp.13998.Peer-Reviewed Original ResearchPost-traumatic stress disorderTrauma-exposed childrenTrauma exposureIntimate partner violencePediatric irritabilityTrauma historyPost-traumatic stress disorder severityPost-traumatic stress disorder symptomsTreatment of irritabilityAdulthood trauma exposureChild trauma exposurePrevalence of irritabilityParent self-reportConnecticut Department of ChildrenParental intimate partner violenceReduce intimate partner violenceFamily unitPTSD severityParental psychopathologyPsychotherapy interventionsStress disorderChild irritabilityPsychiatric symptomsDepartment of ChildrenAssessed pre-interventionHow are irritability and anhedonia symptoms linked? A network approach
Sistiaga S, Tseng W, Zhang L, Rossignol M, Bellaert N. How are irritability and anhedonia symptoms linked? A network approach. Journal Of Clinical Psychology 2024, 80: 1552-1567. PMID: 38497904, DOI: 10.1002/jclp.23679.Peer-Reviewed Original ResearchMajor depressive disorderReward typeSymptoms of major depressive disorderContext of Major Depressive DisorderDimensional Anhedonia Rating ScaleReward processing dysfunctionBrief Irritability TestSymptoms of irritabilityAnhedonia symptomsReward processingDepressive disorderDepression severityProcessing dysfunctionAnhedoniaRating ScaleHedonic responsesExperimental paradigmMultifaceted symptomsRewardEffort dimensionsSymptomsComplex associationsMultiple dimensionsIrritationDepressionIrritability in Youths: A Critical Integrative Review
Leibenluft E, Allen L, Althoff R, Brotman M, Burke J, Carlson G, Dickstein D, Dougherty L, Evans S, Kircanski K, Klein D, Malone E, Mazefsky C, Nigg J, Perlman S, Pine D, Roy A, Salum G, Shakeshaft A, Silver J, Stoddard J, Thapar A, Tseng W, Vidal-Ribas P, Wakschlag L, Stringaris A. Irritability in Youths: A Critical Integrative Review. American Journal Of Psychiatry 2024, 181: 275-290. PMID: 38419494, DOI: 10.1176/appi.ajp.20230256.Peer-Reviewed Original ResearchAttention deficit hyperactivity disorderPathophysiology of irritabilityResponse to frustrationParent management trainingTreating psychological problemsDeficit hyperactivity disorderAutism spectrum disorderPrevalence of irritabilityAssociated with impairmentDiverse longitudinal sampleAssociated with increased risk of anxietyRisk of anxietyYouth irritabilityAnxiety disordersTreating irritabilityHyperactivity disorderBehavior problemsSpectrum disorderDevelopmental trajectoriesAssess irritabilityPsychological problemsLongitudinal sampleImpact of cultural contextTranslational findingsSuicideA Social Process Model of forms of aggression and victimization and internalizing problems
Kawabata Y, Tseng W. A Social Process Model of forms of aggression and victimization and internalizing problems. Journal Of Family Trauma Child Custody & Child Development 2024, ahead-of-print: 1-18. DOI: 10.1080/26904586.2024.2310559.Peer-Reviewed Original ResearchPeer rejectionInternalizing problemsPeer victimizationPhysical aggressionEffects of physical aggressionOne-year longitudinal dataSerial mediation modelAt-risk youthPhysical victimizationRelational victimizationSocial process modelRelational aggressionPublic elementary schoolsVictimsMediation modelDifferential interventionAggressionTaiwanese schoolsElementary schoolSchool yearIndirect effectsSchoolPrevention programsLongitudinal dataPeerPre-scan state anxiety is associated with greater right amygdala-hippocampal response to fearful versus happy faces among trait-anxious Latina girls
Díaz D, Tseng W, Michalska K. Pre-scan state anxiety is associated with greater right amygdala-hippocampal response to fearful versus happy faces among trait-anxious Latina girls. BMC Psychiatry 2024, 24: 1. PMID: 38167015, PMCID: PMC10759434, DOI: 10.1186/s12888-023-05403-6.Peer-Reviewed Original ResearchConceptsState anxietyTrait anxietyHappy facesEmotion processingLatina girlsImplicit emotion processingNon-anxious youthHigh trait anxietyFearful facial affectFearful facesEmotional valenceFacial affectNeural correlatesIndividual differencesBrain activationBrain responsesNeural activationReduced engagementCommunity sampleAnxietyInteractive effectsHigh levelsGirlsMethodsThe present studySystematic differences
2023
Can peripheral psychophysiological markers predict response to exposure-based cognitive behavioral therapy in youth with severely impairing irritability? A study protocol
Grasser L, Erjo T, Goodwin M, Naim R, German R, White J, Cullins L, Tseng W, Stoddard J, Brotman M. Can peripheral psychophysiological markers predict response to exposure-based cognitive behavioral therapy in youth with severely impairing irritability? A study protocol. BMC Psychiatry 2023, 23: 926. PMID: 38082431, PMCID: PMC10712194, DOI: 10.1186/s12888-023-05421-4.Peer-Reviewed Original ResearchConceptsExposure-based cognitive-behavioral therapyCognitive behavioral therapyPhysiological arousalBehavioral therapyAffective Reactivity IndexMultiple baseline trialClinical Global Impression ScaleAnger-inducing stimuliPeripheral physiological indicatorsIndividual differencesPsychophysiological markersPerson changesExposure sessionsMultilevel modelingPsychophysiological indicatorsHR/HRVInitial evidenceMental healthReasons youthReactivity indexYouthAppropriate Institutional Review BoardTreatment mechanismsGlobal Impression ScaleCourse of treatmentPeer functioning difficulties may exacerbate symptoms of attention‐deficit/hyperactivity disorder and irritability over time: a temporal network analysis
Bellaert N, Morreale K, Tseng W. Peer functioning difficulties may exacerbate symptoms of attention‐deficit/hyperactivity disorder and irritability over time: a temporal network analysis. Journal Of Child Psychology And Psychiatry 2023, 65: 809-821. PMID: 37859512, PMCID: PMC11026298, DOI: 10.1111/jcpp.13911.Peer-Reviewed Original ResearchAttention-deficit/hyperactivity disorderPositive social interactionsPeer functioningADHD symptomsIrritability symptomsHyperactivity disorderSocial interactionChild ADHD symptomsSocial-emotional skillsPelham Rating ScaleNegative social environmentsPeer rejectionPeer acceptancePeer nominationsSocial impairmentNovel longitudinal approachPhysical bullyingCommunity samplePoor peerPhysical victimizationInattentionMutual friendshipsLongitudinal associationsTemper outburstsFrequent temper outbursts8.1 Irritability and Trauma Exposure Within the Family System: A Network Approach
Tseng W. 8.1 Irritability and Trauma Exposure Within the Family System: A Network Approach. Journal Of The American Academy Of Child & Adolescent Psychiatry 2023, 62: s336. DOI: 10.1016/j.jaac.2023.07.675.Peer-Reviewed Original ResearchTransactional associations of child irritability and anxiety with parent psychological control in Taiwanese school‐aged children
Lee K, Lebowitz E, Silverman W, Tseng W. Transactional associations of child irritability and anxiety with parent psychological control in Taiwanese school‐aged children. JCPP Advances 2023, 3: e12192. PMID: 38054061, PMCID: PMC10694542, DOI: 10.1002/jcv2.12192.Peer-Reviewed Original ResearchParents’ psychological controlPsychological controlChild irritabilityChild anxietyParent-rated Child Behavior ChecklistIntercept cross-lagged panel modelPsychological Control ScaleCross-lagged panel modelTaiwanese school-aged childrenChild Behavior ChecklistPositive reinforcement techniquesSchool-aged childrenDirect cross-cultural comparisonsPerson processesTransactional associationsPerson levelTransactional pathwaysAnxiety symptomsBehavior ChecklistCommunity sampleCross-cultural comparisonTransactional relationsControl ScaleCollaborative parentingAnxietyAutistic Symptoms, Irritability, and Executive Dysfunctions: Symptom Dynamics from Multi-Network Models
Lee K, Gau S, Tseng W. Autistic Symptoms, Irritability, and Executive Dysfunctions: Symptom Dynamics from Multi-Network Models. Journal Of Autism And Developmental Disorders 2023, 54: 3078-3093. PMID: 37453959, DOI: 10.1007/s10803-023-05981-0.Peer-Reviewed Original ResearchAutism spectrum disorderIrritability symptomsExecutive functionExecutive dysfunctionAutistic symptomsCognitive-behavioral mechanismsSocial communication difficultiesRelative importance networksSample of childrenNeurotypical peersElevated irritabilityASD diagnosisSpectrum disorderBridge symptomsCommunication difficultiesTemper outburstsPredictive pathSymptom dynamicsUnaffected siblingsPartial correlationMoodEntire sampleIrritabilitySpecific relationSymptom nodesAssociations between sleep quality and irritability: Testing the mediating role of emotion regulation
Whiting C, Bellaert N, Deveney C, Tseng W. Associations between sleep quality and irritability: Testing the mediating role of emotion regulation. Personality And Individual Differences 2023, 213: 112322. PMID: 38549685, PMCID: PMC10978035, DOI: 10.1016/j.paid.2023.112322.Peer-Reviewed Original ResearchSleep qualityEmotion regulationPoor sleep qualityMental health disordersMental health difficultiesCommon symptomsPoor sleepPossible intervention targetsSleep problemsHealth disordersDepression symptomsClinical implicationsIrritabilityHealth difficultiesRange of internalizingSelf-report measuresSleepSymptomsIntervention targetsPotential mediatorsConfirmatory factor analysisHigh irritabilityAssociationDirect associationPresent study488. Links Between Neighborhood Resources, Response to Unfairness, and Psychopathology in Youth
Brown B, Peterson O, Nguyen L, Telli O, Morales I, Cardinale E, Tseng W, Kircanski K, Pine D, Leibenluft E, Linke J. 488. Links Between Neighborhood Resources, Response to Unfairness, and Psychopathology in Youth. Biological Psychiatry 2023, 93: s292. DOI: 10.1016/j.biopsych.2023.02.728.Peer-Reviewed Original ResearchNetwork analysis of ecological momentary assessment identifies frustration as a central node in irritability
Tseng W, Naim R, Chue A, Shaughnessy S, Meigs J, Pine D, Leibenluft E, Kircanski K, Brotman M. Network analysis of ecological momentary assessment identifies frustration as a central node in irritability. Journal Of Child Psychology And Psychiatry 2023, 64: 1212-1221. PMID: 36977629, PMCID: PMC10615387, DOI: 10.1111/jcpp.13794.Peer-Reviewed Original Research
2022
Persistent Frustration-Induced Reconfigurations of Brain Networks Predict Individual Differences in Irritability
Linke J, Haller S, Xu E, Nguyen L, Chue A, Botz-Zapp C, Revzina O, Perlstein S, Ross A, Tseng W, Shaw P, Brotman M, Pine D, Gotts S, Leibenluft E, Kircanski K. Persistent Frustration-Induced Reconfigurations of Brain Networks Predict Individual Differences in Irritability. Journal Of The American Academy Of Child & Adolescent Psychiatry 2022, 62: 684-695. PMID: 36563874, PMCID: PMC11224120, DOI: 10.1016/j.jaac.2022.11.009.Peer-Reviewed Original ResearchConceptsResting-state scansPathophysiology of irritabilitySelf-reported irritabilityFunctional magnetic resonance imagingMagnetic resonance imagingParent-reported irritabilitySpecific intervention targetsRisk factorsMotor functionPsychiatric consultationCircuit reorganizationCommon reasonAffective disordersBrain network configurationIrritability symptomsResonance imagingBrain regionsIrritabilityCentral mechanismsAberrant responsesPilot studyIntervention targetsRecovery periodPediatric irritabilityBrain networksAtypical development in white matter microstructures in ADHD: A longitudinal diffusion imaging study
Chiang H, Tseng W, Tseng W, Tung Y, Hsu Y, Chen C, Gau S. Atypical development in white matter microstructures in ADHD: A longitudinal diffusion imaging study. Asian Journal Of Psychiatry 2022, 79: 103358. PMID: 36481569, DOI: 10.1016/j.ajp.2022.103358.Peer-Reviewed Original ResearchConceptsAttention-deficit/hyperactivity disorderInferior fronto-occipital fasciculusGeneralized fractional anisotropyAttention performanceWhite matter microstructureDevelopmental trajectoriesComputerized continuous performance testAtypical developmental trajectoriesContinuous Performance TestDiffusion spectrum imagingFrontal aslant tractWhite matter tractsInattention symptomsAtypical developmentADHD symptomsHyperactivity disorderSuperior longitudinal fasciculusPrefrontal cortexFrontostriatal tractsImaging studiesArcuate fasciculusDevelopmental changesFronto-occipital fasciculusNeuroplastic processesDiagnosis interactionDifferences in white matter segments in autistic males, non-autistic siblings, and non-autistic participants: An intermediate phenotype approach
Chien YL, Chen YJ, Tseng WL, Hsu YC, Wu CS, Tseng WI, Gau SS. Differences in white matter segments in autistic males, non-autistic siblings, and non-autistic participants: An intermediate phenotype approach. Autism 2022, 27: 1036-1052. PMID: 36254873, DOI: 10.1177/13623613221125620.Peer-Reviewed Original ResearchConceptsNon-autistic siblingsNon-autistic peopleAutistic peopleAutistic traitsBrain regionsTheory of mindNon-autistic participantsHigher cognitive functionsAnterior brain regionsSocial cognitionNeurocognitive strengthsNeuropsychological characteristicsCognitive functionAutistic malesDifferent brain regionsAutismBrain adaptationIntermediate phenotype approachWhite matter differencesFuture researchNeural pathwaysBiological basisPeopleSiblingsCausal linkDevelopmental Milestones of Infancy and Associations with Later Childhood Neurodevelopmental Outcomes in the Adolescent Brain Cognitive Development (ABCD) Study
Zhuo H, Xiao J, Tseng WL, Liew Z. Developmental Milestones of Infancy and Associations with Later Childhood Neurodevelopmental Outcomes in the Adolescent Brain Cognitive Development (ABCD) Study. Children 2022, 9: 1424. PMID: 36291360, PMCID: PMC9600325, DOI: 10.3390/children9101424.Peer-Reviewed Original ResearchAdolescent Brain Cognitive Development (ABCD) studyCognitive Development StudyNeurocognitive functionLanguage milestonesBehavioral problemsDevelopmental milestonesBrief Problem MonitorBiological mothersPoorer neurocognitive functionNeurobehavioral outcomesDevelopment studiesNIH ToolboxFirst wordBehavioral outcomesDiverse sampleLinear mixed effects modelsLater neurodevelopmental outcomeMixed effects modelsChildrenNeurodevelopmental outcomesWorse neurocognitive functionChildhood neurodevelopmental outcomesInfancyResearch assistantsPercentile of ageSystematic Review and Meta-analysis: Task-based fMRI Studies in Youths With Irritability
Lee KS, Hagan CN, Hughes M, Cotter G, Freud E, Kircanski K, Leibenluft E, Brotman MA, Tseng WL. Systematic Review and Meta-analysis: Task-based fMRI Studies in Youths With Irritability. Journal Of The American Academy Of Child & Adolescent Psychiatry 2022, 62: 208-229. PMID: 35944754, PMCID: PMC9892288, DOI: 10.1016/j.jaac.2022.05.014.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingFMRI studyNeurocognitive functionNeural convergenceActivation likelihood estimationLow frustration toleranceIrritability measuresFrequent temper tantrumsSample characteristicsCognitive controlFMRI taskEmotional reactivityStimulus typeFMRI resultsChildhood irritabilityFrustration toleranceNeural mechanismsFunctional neuroimagingTransdiagnostic symptomsTask domainTemper tantrumsFMRI methodsNeuroscience databasesNull findingsCoordinate-based dataCharacterizing the Neural Correlates of Response Inhibition and Error Processing in Children With Symptoms of Irritability and/or Attention-Deficit/Hyperactivity Disorder in the ABCD Study®
Lee KS, Xiao J, Luo J, Leibenluft E, Liew Z, Tseng WL. Characterizing the Neural Correlates of Response Inhibition and Error Processing in Children With Symptoms of Irritability and/or Attention-Deficit/Hyperactivity Disorder in the ABCD Study®. Frontiers In Psychiatry 2022, 13: 803891. PMID: 35308882, PMCID: PMC8931695, DOI: 10.3389/fpsyt.2022.803891.Peer-Reviewed Original ResearchAttention-deficit/hyperactivity disorderResponse inhibitionError processingNeural correlatesIrritability symptomsHyperactivity disorderHigher attention-deficit/hyperactivity disorderAdolescent Brain Cognitive Development (ABCD) studySymptoms of inattentionDifferential neural mechanismsCognitive Development StudyStop-signal taskLow frustration toleranceLatent class analysisFronto-parietal regionsLatent variable modelingPediatric irritabilityNeural differencesIndividual differencesSignal taskExecutive dysfunctionFrustration toleranceNeural mechanismsABCD studyHigh irritability