2023
Can peripheral psychophysiological markers predict response to exposure-based cognitive behavioral therapy in youth with severely impairing irritability? A study protocol
Grasser L, Erjo T, Goodwin M, Naim R, German R, White J, Cullins L, Tseng W, Stoddard J, Brotman M. Can peripheral psychophysiological markers predict response to exposure-based cognitive behavioral therapy in youth with severely impairing irritability? A study protocol. BMC Psychiatry 2023, 23: 926. PMID: 38082431, PMCID: PMC10712194, DOI: 10.1186/s12888-023-05421-4.Peer-Reviewed Original ResearchConceptsExposure-based cognitive-behavioral therapyCognitive behavioral therapyPhysiological arousalBehavioral therapyAffective Reactivity IndexMultiple baseline trialClinical Global Impression ScaleAnger-inducing stimuliPeripheral physiological indicatorsIndividual differencesPsychophysiological markersPerson changesExposure sessionsMultilevel modelingPsychophysiological indicatorsHR/HRVInitial evidenceMental healthReasons youthReactivity indexYouthAppropriate Institutional Review BoardTreatment mechanismsGlobal Impression ScaleCourse of treatment
2015
BEHAVIOR AND EMOTION MODULATION DEFICITS IN PRESCHOOLERS AT RISK FOR BIPOLAR DISORDER
Tseng W, Guyer AE, Briggs‐Gowan M, Axelson D, Birmaher B, Egger HL, Helm J, Stowe Z, Towbin KA, Wakschlag LS, Leibenluft E, Brotman MA. BEHAVIOR AND EMOTION MODULATION DEFICITS IN PRESCHOOLERS AT RISK FOR BIPOLAR DISORDER. Depression And Anxiety 2015, 32: 325-334. PMID: 25691090, PMCID: PMC4409452, DOI: 10.1002/da.22342.Peer-Reviewed Original ResearchConceptsBipolar disorderAppropriate clinical assessment toolFamilial riskLow-risk groupFirst-degree relativesClinical assessment toolHigh familial riskStandardized laboratory observationsOppositional defiant disorderFamily historyMood disordersModulation deficitsLower riskProdromal indicatorsPsychiatric assessmentChild Behavior ChecklistEarly interventionAnger modulationDefiant disorderDisordersLarge longitudinal sampleHigh-risk preschoolersBehavior ChecklistRiskEmotional problems