2018
Effects of Varenicline on Cognitive Performance in Heavy Drinkers: Dose-Response Effects and Associations With Drinking Outcomes
Roberts W, McKee SA. Effects of Varenicline on Cognitive Performance in Heavy Drinkers: Dose-Response Effects and Associations With Drinking Outcomes. Experimental And Clinical Psychopharmacology 2018, 26: 49-57. PMID: 29389170, PMCID: PMC5797996, DOI: 10.1037/pha0000161.Peer-Reviewed Original ResearchConceptsAlcohol use disorderCognitive functioningCognitive assessment batteryContinuous performance taskAdult heavy drinkersSignificant indirect effectUse disordersReaction timeEffects of vareniclinePerformance taskHeavy drinkersCognitive outcomesAssessment BatteryHuman laboratory experimentsCognitive functionMediation analysisDrinking outcomesMemoryLess drinkingAlcohol useDrinking behaviorIndirect effectsLaboratory sessionsDrinking taskVarenicline dose
2017
Effects of varenicline on alcohol cue reactivity in heavy drinkers
Roberts W, Harrison ELR, McKee SA. Effects of varenicline on alcohol cue reactivity in heavy drinkers. Psychopharmacology 2017, 234: 2737-2745. PMID: 28600734, PMCID: PMC5709183, DOI: 10.1007/s00213-017-4667-9.Peer-Reviewed Original ResearchConceptsEffects of vareniclineHuman laboratory studiesAlcohol use disorderAlcohol cue reactivityHeavy drinkersUse disordersPlacebo-controlled human laboratory studyCue exposureAlcohol useCue reactivityUse of vareniclineFront-line treatmentCue-induced alcohol cravingAlcohol cue exposureTitration periodCue-reactivity paradigmMedication groupPharmacological treatmentMedication effectsAdult smokersTobacco cravingVareniclineMethodsAs partLarge seriesAlcohol craving