The liver as a site of T‐cell apoptosis: graveyard, or killing field?
Crispe I, Dao T, Klugewitz K, Mehal W, Metz D. The liver as a site of T‐cell apoptosis: graveyard, or killing field? Immunological Reviews 2000, 174: 47-62. PMID: 10807506, DOI: 10.1034/j.1600-0528.2002.017412.x.Peer-Reviewed Original ResearchMeSH KeywordsAdoptive TransferAnimalsAntigensApoptosisCD8-Positive T-LymphocytesCell AdhesionEndothelium, VascularFas ReceptorHepatitis CHumansImmune ToleranceImmunophenotypingIntestinal AbsorptionKiller Cells, NaturalKupffer CellsLiverLiver CirculationLiver TransplantationLymphocyte ActivationLymphocyte SubsetsMiceMice, TransgenicModels, ImmunologicalPortal VeinConceptsT cellsNatural killerT cell trappingNK T cellsPeripheral immune responsePortal vein infusionApoptotic T cellsT cell apoptosisNormal mouse liverPhenomenon of toleranceApoptotic CD8Liver allograftsOral toleranceHepatitis C.Lymphocyte populationsAntigenic cellsImmune responseLiver pathogensVein infusionClearance phaseLiver resultsLiverDirect perfusionMouse liverCell populations