HOS2 and HDA1 Encode Histone Deacetylases with Opposing Roles in Candida albicans Morphogenesis
Zacchi LF, Schulz WL, Davis DA. HOS2 and HDA1 Encode Histone Deacetylases with Opposing Roles in Candida albicans Morphogenesis. PLOS ONE 2010, 5: e12171. PMID: 20730094, PMCID: PMC2921335, DOI: 10.1371/journal.pone.0012171.Peer-Reviewed Original ResearchMeSH KeywordsCandida albicansHistone DeacetylasesHydrogen-Ion ConcentrationHyphaeMutagenesisMutationConceptsHistone deacetylasesHuman fungal pathogen Candida albicansFungal pathogen Candida albicansHuman pathogen C. albicansVirulence traitsRole of HDACsWhite-opaque switchingC. albicans morphogenesisCandida albicans MorphogenesisPathogen Candida albicansYeast-hyphal transitionCritical virulence attributeDifferent environmental stimuliPathogen C. albicansMorphogenetic transitionEpigenetic mechanismsHyphal formationC. albicansHos2Diverse pathogensMorphogenesisEnvironmental stimuliVirulence attributesHOS1Opposing roles