Featured Publications
From Data to Wisdom: Biomedical Knowledge Graphs for Real-World Data Insights
Hänsel K, Dudgeon S, Cheung K, Durant T, Schulz W. From Data to Wisdom: Biomedical Knowledge Graphs for Real-World Data Insights. Journal Of Medical Systems 2023, 47: 65. PMID: 37195430, PMCID: PMC10191934, DOI: 10.1007/s10916-023-01951-2.Commentaries, Editorials and LettersConceptsKnowledge graphReal-world dataGraph modelBiomedical data integrationGraph data modelIntegrated Knowledge GraphBiomedical knowledge graphsElectronic health recordsData integrationData insightsData modelInsight generationBiomedical informationHealth recordsArt researchGraphNovel approachCombination of dataDisease phenotypingInformationPrecision medicine researchHealthcareIntegrationEHRIntriguing opportunityTemporal relationship of computed and structured diagnoses in electronic health record data
Schulz WL, Young HP, Coppi A, Mortazavi BJ, Lin Z, Jean RA, Krumholz HM. Temporal relationship of computed and structured diagnoses in electronic health record data. BMC Medical Informatics And Decision Making 2021, 21: 61. PMID: 33596898, PMCID: PMC7890604, DOI: 10.1186/s12911-021-01416-x.Peer-Reviewed Original ResearchConceptsElectronic health recordsStructured diagnosisOutpatient blood pressureElectronic health record dataAcademic health systemLow-density lipoproteinHealth record dataBlood pressureStructured data elementsAdministrative claimsHypertensionClinical informationHyperlipidemiaClinical phenotypeEquivalent diagnosisVital signsHealth systemDiagnosisProblem listAdditional studiesHealth recordsRecord dataTimely accessEHR dataPatients
2024
Hypertension Trends and Disparities Over 12 Years in a Large Health System: Leveraging the Electronic Health Records
Brush J, Lu Y, Liu Y, Asher J, Li S, Sawano M, Young P, Schulz W, Anderson M, Burrows J, Krumholz H. Hypertension Trends and Disparities Over 12 Years in a Large Health System: Leveraging the Electronic Health Records. Journal Of The American Heart Association 2024, 13: e033253. PMID: 38686864, PMCID: PMC11179912, DOI: 10.1161/jaha.123.033253.Peer-Reviewed Original ResearchConceptsElectronic health recordsRegional health systemImprove hypertension careHealth systemHealth recordsHypertension careDiastolic blood pressureAge-adjusted prevalence ratesNon-Hispanic Black patientsPrevalence ratesLarger health systemCross-sectional analysisTransformation of medical dataLeveraging real-world dataHigh prevalence rateHypertension trendsHypertension prevalenceBlood pressureBlood pressure measurementsHypertension diagnosisPrimary outcomeNational trendsProportion of patientsAntihypertensive medicationsBlack patients
2021
Feasibility of capturing real-world data from health information technology systems at multiple centers to assess cardiac ablation device outcomes: A fit-for-purpose informatics analysis report
Jiang G, Dhruva SS, Chen J, Schulz WL, Doshi AA, Noseworthy PA, Zhang S, Yu Y, Young H, Brandt E, Ervin KR, Shah ND, Ross JS, Coplan P, Drozda JP. Feasibility of capturing real-world data from health information technology systems at multiple centers to assess cardiac ablation device outcomes: A fit-for-purpose informatics analysis report. Journal Of The American Medical Informatics Association 2021, 28: 2241-2250. PMID: 34313748, PMCID: PMC8449615, DOI: 10.1093/jamia/ocab117.Peer-Reviewed Original ResearchConceptsReal-world dataHealth information technology systemsInformation technology systemsUnique device identifiersMaturity modelNatural language processing toolsTechnology systemsUnstructured data elementsNatural language processingCommon data modelData quality frameworkLanguage processing toolsComputable phenotypeInformatics approachElectronic health recordsClinical data systemsData modelLanguage processingDevice identifiersStandardized codesData elementsProcessing toolsInformatics technologiesData captureHealth records
2020
Leveraging the Electronic Health Records for Population Health: A Case Study of Patients With Markedly Elevated Blood Pressure
Lu Y, Huang C, Mahajan S, Schulz WL, Nasir K, Spatz ES, Krumholz HM. Leveraging the Electronic Health Records for Population Health: A Case Study of Patients With Markedly Elevated Blood Pressure. Journal Of The American Heart Association 2020, 9: e015033. PMID: 32200730, PMCID: PMC7428633, DOI: 10.1161/jaha.119.015033.Peer-Reviewed Original ResearchConceptsDiastolic blood pressureSystolic blood pressureElevated blood pressureBlood pressureElectronic health recordsPopulation health surveillanceHealth recordsYale New Haven Health SystemHealth surveillanceHealth systemPatterns of patientsLarge health systemUsual careOutpatient encountersControl ratePatientsCare patternsPopulation healthMonthsHgSurveillancePrevalenceRecordsVisitsCare