2007
Protein requirements for sister telomere association in human cells
Canudas S, Houghtaling BR, Kim JY, Dynek JN, Chang WG, Smith S. Protein requirements for sister telomere association in human cells. The EMBO Journal 2007, 26: 4867-4878. PMID: 17962804, PMCID: PMC2099466, DOI: 10.1038/sj.emboj.7601903.Peer-Reviewed Original ResearchCell Cycle ProteinsCentrifugation, Density GradientChromosomal Proteins, Non-HistoneGene Expression Regulation, NeoplasticHeLa CellsHumansImmunoprecipitationIn Situ Hybridization, FluorescenceMitosisModels, BiologicalNuclear ProteinsPoly(ADP-ribose) PolymerasesProtein BindingTankyrasesTelomereTelomere-Binding ProteinsTelomeric Repeat Binding Protein 1
2002
Role for the Related Poly(ADP-Ribose) Polymerases Tankyrase 1 and 2 at Human Telomeres
Cook BD, Dynek JN, Chang W, Shostak G, Smith S. Role for the Related Poly(ADP-Ribose) Polymerases Tankyrase 1 and 2 at Human Telomeres. Molecular And Cellular Biology 2002, 22: 332-342. PMID: 11739745, PMCID: PMC134233, DOI: 10.1128/mcb.22.1.332-342.2002.Peer-Reviewed Original ResearchConceptsTankyrase 2Tankyrase 1Telomeric complexTelomeric DNA-binding proteinAccess of telomerasePolymerase tankyrase 1DNA-binding proteinsSpecialized reverse transcriptaseEndogenous TRF1Telomere maintenanceTelomeric functionPrimary human cellsRelated homologsPARP domainTelomeric DNAHuman telomeresTRF1TelomeresHuman cellsADP-ribosylationPARP assaysRecent identificationTelomeraseReverse transcriptaseOverexpression