2023
Towards a youth mental health paradigm: a perspective and roadmap
Uhlhaas P, Davey C, Mehta U, Shah J, Torous J, Allen N, Avenevoli S, Bella-Awusah T, Chanen A, Chen E, Correll C, Do K, Fisher H, Frangou S, Hickie I, Keshavan M, Konrad K, Lee F, Liu C, Luna B, McGorry P, Meyer-Lindenberg A, Nordentoft M, Öngür D, Patton G, Paus T, Reininghaus U, Sawa A, Schoenbaum M, Schumann G, Srihari V, Susser E, Verma S, Woo T, Yang L, Yung A, Wood S. Towards a youth mental health paradigm: a perspective and roadmap. Molecular Psychiatry 2023, 28: 3171-3181. PMID: 37580524, PMCID: PMC10618105, DOI: 10.1038/s41380-023-02202-z.Peer-Reviewed Original ResearchConceptsMental disordersSevere mental disordersEarly intervention paradigmYears of ageMost mental disordersEarly diagnosisEmergence of psychopathologyClinical careTypical onsetProtective factorsBrain developmentMental healthDiagnosisDisordersHealth paradigmMental health paradigmPsychopathologyIntervention paradigmPathogenesisYoung peopleCarePrevention
2016
The NF-κB signaling pathway: an important therapeutic target in psychiatric disorders
Altinoz MA, Ince B, Tek C, Srihari VH, Guloksuz S. The NF-κB signaling pathway: an important therapeutic target in psychiatric disorders. Molecular Psychiatry 2016, 23: 490-491. PMID: 27843154, DOI: 10.1038/mp.2016.207.Peer-Reviewed Original ResearchThe Connecticut Mental Health Center: Celebrating 50 Years of a Successful Partnership Between the State and Yale University
Steiner JL, Anez-Nava L, Baranoski M, Cole R, Davidson L, Delphin-Rittmon M, Dike C, DiLeo PJ, Duman RS, Kirk T, Krystal J, Malison RT, Rohrbaugh RM, Sernyak MJ, Srihari V, Styron T, Tebes JK, Woods S, Zonana H, Jacobs SC. The Connecticut Mental Health Center: Celebrating 50 Years of a Successful Partnership Between the State and Yale University. Psychiatric Services 2016, 67: 1286-1289. PMID: 27691379, DOI: 10.1176/appi.ps.201600373.Peer-Reviewed Original ResearchMeSH KeywordsAcademic Medical CentersConnecticutCooperative BehaviorEducationHospitals, PsychiatricHumansMental DisordersPsychiatryUniversities
2013
Investigating the safety and efficacy of naltrexone for anti-psychotic induced weight gain in severe mental illness: study protocol of a double-blind, randomized, placebo-controlled trial
Tek C, Guloksuz S, Srihari VH, Reutenauer EL. Investigating the safety and efficacy of naltrexone for anti-psychotic induced weight gain in severe mental illness: study protocol of a double-blind, randomized, placebo-controlled trial. BMC Psychiatry 2013, 13: 176. PMID: 23805859, PMCID: PMC3702521, DOI: 10.1186/1471-244x-13-176.Peer-Reviewed Original ResearchConceptsSevere mental illnessEfficacy of naltrexoneWeight gainOutcome measurementsHealth problemsMental illnessGreater New Haven areaTumor necrosis factor alphaWeight lossCurrent available medicationsPlacebo-controlled trialHigh-sensitivity CRPOpioid receptor antagonistSecondary outcome measuresSerum lipid profilePrimary outcome measurementBody mass indexD2 receptor blockadeEffects of naltrexoneNovel pharmacological optionsNecrosis factor alphaDoses of naltrexoneMajor health problemRates of obesitySignificant weight loss
2010
Mediators and moderators in early intervention research
Breitborde NJ, Srihari VH, Pollard JM, Addington DN, Woods SW. Mediators and moderators in early intervention research. Early Intervention In Psychiatry 2010, 4: 143-152. PMID: 20536970, PMCID: PMC4469902, DOI: 10.1111/j.1751-7893.2010.00177.x.Peer-Reviewed Original Research
2006
Gained in Translation: Evidence-Based Medicine Meets Pediatric Psychopharmacology
Srihari V, Martin A. Gained in Translation: Evidence-Based Medicine Meets Pediatric Psychopharmacology. Child And Adolescent Psychiatric Clinics Of North America 2006, 15: 263-287. PMID: 16321734, DOI: 10.1016/j.chc.2005.08.001.Peer-Reviewed Original Research