2002
Schizosaccharomyces pombe pfh1+Encodes an Essential 5′ to 3′ DNA Helicase That Is a Member of thePIF1 Subfamily of DNA Helicases
Zhou J, Qi H, Schulz V, Mateyak M, Monson E, Zakian V. Schizosaccharomyces pombe pfh1+Encodes an Essential 5′ to 3′ DNA Helicase That Is a Member of thePIF1 Subfamily of DNA Helicases. Molecular Biology Of The Cell 2002, 13: 2180-2191. PMID: 12058079, PMCID: PMC117634, DOI: 10.1091/mbc.02-02-0021.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsDNA HelicasesDNA PrimersDNA, MitochondrialDNA, RibosomalDNA-Binding ProteinsHumansMolecular Sequence DataPolycomb-Group ProteinsProteinsRestriction MappingSaccharomyces cerevisiae ProteinsSchizosaccharomycesSchizosaccharomyces pombe ProteinsTranscription FactorsConceptsS. pombe proteinPombe proteinsDNA helicaseHelicase activityTelomeric DNAS. cerevisiaeATPase/helicase activitySchizosaccharomyces pombe geneSole essential functionDNA helicase activityInvariant lysine residuePombe geneDNA helicasesMitochondrial DNADNA replicationMutant sporesCellular phenotypesHigh identityGenetic analysisEssential functionsSame phenotypePrototype memberHelicaseLysine residuesS phase
1994
The saccharomyces PIF1 DNA helicase inhibits telomere elongation and de novo telomere formation
Schulz V, Zakian V. The saccharomyces PIF1 DNA helicase inhibits telomere elongation and de novo telomere formation. Cell 1994, 76: 145-155. PMID: 8287473, DOI: 10.1016/0092-8674(94)90179-1.Peer-Reviewed Original ResearchConceptsSubtelomeric genesDNA helicaseDe novoPif1 DNA helicaseYeast mutantsPif1 helicaseNew telomeresPif1 mutantsTelomere elongationTelomeric DNASubtelomeric regionsLittle homologyLoss of expressionChromosome breakageHelicaseGenesPIF1MutantsTelomeresNovoMutationsElevated frequencyExpressionCellsChromosomes
1991
Translation initiation of IS50R read-through transcripts
Schulz V, Reznikoff W. Translation initiation of IS50R read-through transcripts. Journal Of Molecular Biology 1991, 221: 65-80. PMID: 1717696, DOI: 10.1016/0022-2836(91)80205-9.Peer-Reviewed Original ResearchConceptsRNA secondary structureTranslation initiationSecondary structureRibosome binding siteRNA secondary structure analysisPotential RNA secondary structureSecondary structure analysisEffects of mutationsTransposase proteinTransposase geneIS50RNormal transcriptTransposase expressionTranscriptsInsertion sequenceBinding sitesMutationsGenesTransposaseReadsStructure analysisProteinOuter endLow levelsSequence
1990
In vitro secondary structure analysis of mRNA from lacZ translation initiation mutants
Schulz V, Reznikoff W. In vitro secondary structure analysis of mRNA from lacZ translation initiation mutants. Journal Of Molecular Biology 1990, 211: 427-445. PMID: 2106583, DOI: 10.1016/0022-2836(90)90363-q.Peer-Reviewed Original ResearchConceptsTranslation initiation regionSecondary structure analysisStem-loop structureTranslation initiationSecondary structureRNA transcriptsInitiation regionMRNA secondary structureTranslation initiation efficiencyRNA secondary structureInitiation mutantMutant RNAsStructure analysisRNATranscriptsMutations