Primitive Erythroid Progenitors Are Regulated by Hypoxia and Display An Aerobic Glycolytic Metabolic Profile,
Baron M, Isern J, Fraser S, He Z, Ma'ayan A, Schulz V, Tuck D, Gallagher P. Primitive Erythroid Progenitors Are Regulated by Hypoxia and Display An Aerobic Glycolytic Metabolic Profile,. Blood 2011, 118: 3159. DOI: 10.1182/blood.v118.21.3159.3159.Peer-Reviewed Original ResearchErythroid developmentGenome-wide expression profilingErythroid cell fateCandidate transcriptional regulatorsCell typesHIF-1Transcription factor HIF-1Early mouse embryosMouse yolk sacNumber of genesHIF-1 target genesMost mammalian cellsAnalysis of promotersYolk sacDominant negative regulatorGlycolytic metabolic profileStem/progenitorsPrimitive erythropoiesisPrimitive erythroid progenitorsMesodermal progenitorsCell fateTranscriptional regulatorsTranscription profilingMammalian embryosKinase network