1997
Telomere Length Regulation by the Pif1 DNA Helicase
Monson E, Schulz V, Zakian V. Telomere Length Regulation by the Pif1 DNA Helicase. Pezcoller Foundation Symposia 1997, 97-110. DOI: 10.1007/978-1-4615-5365-6_7.Peer-Reviewed Original ResearchConventional replication machineryLinear eukaryotic chromosomesPif1 DNA helicaseProtein-DNA structuresConventional DNA polymerasesDNA polymeraseBroken chromosome endsUnique reverse transcriptaseEnds of chromosomesDNA replication enzymeCell cycle arrestEukaryotic chromosomesChromosome endsDNA helicaseLinear chromosomesUnreplicated DNAIntact chromosomesLength regulationReplication machineryTelomeric DNAReplication enzymesRNA primersCell cycleChromosomesStable maintenance
1994
The saccharomyces PIF1 DNA helicase inhibits telomere elongation and de novo telomere formation
Schulz V, Zakian V. The saccharomyces PIF1 DNA helicase inhibits telomere elongation and de novo telomere formation. Cell 1994, 76: 145-155. PMID: 8287473, DOI: 10.1016/0092-8674(94)90179-1.Peer-Reviewed Original ResearchConceptsSubtelomeric genesDNA helicaseDe novoPif1 DNA helicaseYeast mutantsPif1 helicaseNew telomeresPif1 mutantsTelomere elongationTelomeric DNASubtelomeric regionsLittle homologyLoss of expressionChromosome breakageHelicaseGenesPIF1MutantsTelomeresNovoMutationsElevated frequencyExpressionCellsChromosomes