2000
Pif1p Helicase, a Catalytic Inhibitor of Telomerase in Yeast
Zhou J, Monson E, Teng S, Schulz V, Zakian V. Pif1p Helicase, a Catalytic Inhibitor of Telomerase in Yeast. Science 2000, 289: 771-774. PMID: 10926538, DOI: 10.1126/science.289.5480.771.Peer-Reviewed Original ResearchMeSH KeywordsAllelesAmino Acid MotifsAnimalsCatalysisCell LineChromosomes, FungalDNA DamageDNA HelicasesDNA ReplicationDNA, FungalGene ExpressionHumansMutagenesis, Site-DirectedPoint MutationRecombinant ProteinsRecombination, GeneticSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSequence Homology, Amino AcidTelomeraseTelomere
1994
The saccharomyces PIF1 DNA helicase inhibits telomere elongation and de novo telomere formation
Schulz V, Zakian V. The saccharomyces PIF1 DNA helicase inhibits telomere elongation and de novo telomere formation. Cell 1994, 76: 145-155. PMID: 8287473, DOI: 10.1016/0092-8674(94)90179-1.Peer-Reviewed Original ResearchConceptsSubtelomeric genesDNA helicaseDe novoPif1 DNA helicaseYeast mutantsPif1 helicaseNew telomeresPif1 mutantsTelomere elongationTelomeric DNASubtelomeric regionsLittle homologyLoss of expressionChromosome breakageHelicaseGenesPIF1MutantsTelomeresNovoMutationsElevated frequencyExpressionCellsChromosomes
1991
Translation initiation of IS50R read-through transcripts
Schulz V, Reznikoff W. Translation initiation of IS50R read-through transcripts. Journal Of Molecular Biology 1991, 221: 65-80. PMID: 1717696, DOI: 10.1016/0022-2836(91)80205-9.Peer-Reviewed Original ResearchConceptsRNA secondary structureTranslation initiationSecondary structureRibosome binding siteRNA secondary structure analysisPotential RNA secondary structureSecondary structure analysisEffects of mutationsTransposase proteinTransposase geneIS50RNormal transcriptTransposase expressionTranscriptsInsertion sequenceBinding sitesMutationsGenesTransposaseReadsStructure analysisProteinOuter endLow levelsSequence
1990
In vitro secondary structure analysis of mRNA from lacZ translation initiation mutants
Schulz V, Reznikoff W. In vitro secondary structure analysis of mRNA from lacZ translation initiation mutants. Journal Of Molecular Biology 1990, 211: 427-445. PMID: 2106583, DOI: 10.1016/0022-2836(90)90363-q.Peer-Reviewed Original ResearchConceptsTranslation initiation regionSecondary structure analysisStem-loop structureTranslation initiationSecondary structureRNA transcriptsInitiation regionMRNA secondary structureTranslation initiation efficiencyRNA secondary structureInitiation mutantMutant RNAsStructure analysisRNATranscriptsMutations