2024
Racial Implicit Associations in Child Psychiatry
Malison K, Avila-Quintero V, Al-Mateen C, Flores J, Landeros Weisenberger A, Njoroge W, Novins D, Robles-Ramamurthy B, Taylor J, Bloch M, Tobón A. Racial Implicit Associations in Child Psychiatry. Journal Of The American Academy Of Child & Adolescent Psychiatry 2024 PMID: 38823476, DOI: 10.1016/j.jaac.2024.04.013.Peer-Reviewed Original ResearchImplicit Association TestRace Implicit Association TestRecruitment of human participantsExternalizing behavior problemsPaper self-identifiesImplicit associationsChildren faceBehavior problemsChild psychiatryAbstractText Label="DIVERSITY &Negatively valenced wordsExternal wordHuman participantsValenced wordsExternalizing disordersParticipating psychiatristsPsychiatric cliniciansNegative valenceNegative wordsPsychiatristsAssociation TestPsychiatryInvestigate psychiatristsReduce racial inequalityDemographic predictorsTreatment Outcomes With Licensed and Unlicensed Stimulant Doses for Adults With Attention-Deficit/Hyperactivity Disorder
Farhat L, Flores J, Avila-Quintero V, Polanczyk G, Cipriani A, Furukawa T, Bloch M, Cortese S. Treatment Outcomes With Licensed and Unlicensed Stimulant Doses for Adults With Attention-Deficit/Hyperactivity Disorder. JAMA Psychiatry 2024, 81: 157-166. PMID: 37878348, PMCID: PMC10600727, DOI: 10.1001/jamapsychiatry.2023.3985.Peer-Reviewed Original ResearchAttention-deficit/hyperactivity disorderLicensed dosesDose-response curveStimulant dosesClinical trialsTreatment outcomesRisk benefitHyperactivity disorderReduction of symptomsDrug Administration recommendationsAdverse eventsDose escalationLanguage restrictionsAdministration recommendationsUS FoodSymptomsDosesAdditional riskData extractionAdditional reductionADHD symptomsAdultsGreater reductionStimulantsRiskExploring Predictors of Ketamine Response in Adolescent Treatment-Resistant Depression
Lineham A, Avila-Quintero V, Bloch M, Dwyer J. Exploring Predictors of Ketamine Response in Adolescent Treatment-Resistant Depression. Journal Of Child And Adolescent Psychopharmacology 2024, 34: 73-79. PMID: 38170185, PMCID: PMC11262580, DOI: 10.1089/cap.2023.0047.Peer-Reviewed Original ResearchDepression symptom improvementTreatment-resistant depressionChildren's Depression Rating ScaleReuptake inhibitor medicationsDepression Rating ScaleSymptom improvementAntidepressant responseInhibitor medicationKetamine responseAdolescent treatment-resistant depressionRapid-acting antidepressant agentsSelective serotonin reuptake inhibitor medicationsSerotonin reuptake inhibitor medicationsKetamine’s antidepressant responseCurrent depressive episodeSevere depressive symptomsGreater symptom improvementAttention-deficit/hyperactivity disorder diagnosisFuture therapeutic useAntidepressant medicationMedication trialsCrossover trialAntidepressant agentsClinical variablesDepressive episode
2023
Pharmacological and Somatic Treatment Effects on Suicide in Adults: A Systematic Review and Meta-Analysis
Wilkinson S, Diaz D, Rupp Z, Kidambi A, Ramirez K, Flores J, Avila‐Quintero V, Rhee T, Olfson M, Bloch M. Pharmacological and Somatic Treatment Effects on Suicide in Adults: A Systematic Review and Meta-Analysis. FOCUS The Journal Of Lifelong Learning In Psychiatry 2023, 21: 197-208. PMID: 37201149, PMCID: PMC10172559, DOI: 10.1176/appi.focus.23021006.Peer-Reviewed Original ResearchOdds of suicidePlacebo/Suicide riskPsychotic disordersBipolar disorderSuicide deathsMeta-analyzed associationsNon-clozapine antipsychoticsMagnetic seizure therapySomatic interventionsVagus nerve stimulationNewcastle-Ottawa ScaleAntiepileptic mood stabilizersTranscranial magnetic stimulationCertain clinical contextsDirect current stimulationEffects of pharmacologicPublic health crisisElectroconvulsive therapySeizure therapyNerve stimulationMood stabilizersStudy qualityProtective effectMagnetic stimulationThe Relationship Between Acute Dissociative Effects Induced by Ketamine and Treatment Response in Adolescent Patients with Treatment-Resistant Depression
Lineham A, Avila-Quintero V, Bloch M, Dwyer J. The Relationship Between Acute Dissociative Effects Induced by Ketamine and Treatment Response in Adolescent Patients with Treatment-Resistant Depression. Journal Of Child And Adolescent Psychopharmacology 2023, 33: 20-26. PMID: 36799961, DOI: 10.1089/cap.2022.0086.Peer-Reviewed Original ResearchConceptsTreatment-resistant depressionDepression symptom improvementAcute dissociative symptomsAntidepressant responseSymptom improvementRapid-acting antidepressant agentsSignificant associationDissociative symptomsLikelihood of responseDissociation symptomsMagnitude of associationDissociative effectsKetamine groupPediatric patientsCrossover trialPediatric populationAntidepressant agentsKetamine responseAdolescent patientsAdult studiesDepression responseSecondary data analysisTreatment responseDepressive symptomsTrial designSystematic review and meta-analysis: Season of birth and schizophrenia risk
Coury S, Lombroso A, Avila-Quintero V, Taylor J, Flores J, Szejko N, Bloch M. Systematic review and meta-analysis: Season of birth and schizophrenia risk. Schizophrenia Research 2023, 252: 244-252. PMID: 36682315, DOI: 10.1016/j.schres.2022.12.016.Peer-Reviewed Original ResearchConceptsRisk of schizophreniaSummer birthWinter birthSystematic reviewBirth monthVitamin D deficiencyStratified subgroup analysisSchizophrenia riskEtiological risk factorsMonth of birthD deficiencySeason of birthEtiologic causesSubgroup analysisVirus exposureRisk factorsSchizophreniaMonthsBirthSignificant differencesRiskAssociationAssociation Between Patient Race and Ethnicity and Outcomes With COVID-19: A Retrospective Analysis From a Large Mid-Atlantic Health System
Rao A, Alnababteh M, Avila-Quintero V, Flores J, Laing N, Boyd D, Yu J, Ahmed N, Groninger H, Zaaqoq A. Association Between Patient Race and Ethnicity and Outcomes With COVID-19: A Retrospective Analysis From a Large Mid-Atlantic Health System. Journal Of Intensive Care Medicine 2023, 38: 472-478. PMID: 36594202, PMCID: PMC9813659, DOI: 10.1177/08850666221149956.Peer-Reviewed Original ResearchConceptsHispanic patientsWhite patientsClinical outcomesMechanical ventilationAverage ageSevere COVID-19 infectionRetrospective cohort studyCOVID-19 pneumoniaOdds of deathPatient demographic dataCOVID-19 infectionNon-Hispanic blacksCOVID-19Non-Hispanic whitesElectronic health recordsCohort studyPatient raceDecreased oddsRetrospective analysisProfit healthcare systemStudy populationPatientsLower average ageLower mortalityDemographic data
2022
Social media use and body image issues among adolescents in a vulnerable Louisiana community
Sagrera C, Magner J, Temple J, Lawrence R, Magner T, Avila-Quintero V, McPherson P, Alderman L, Bhuiyan M, Patterson J, Murnane K. Social media use and body image issues among adolescents in a vulnerable Louisiana community. Frontiers In Psychiatry 2022, 13: 1001336. PMID: 36405904, PMCID: PMC9669337, DOI: 10.3389/fpsyt.2022.1001336.Peer-Reviewed Original ResearchSexual Orientation and Racial Bias in Relation to Medical Specialty
Zelin NS, Scott C, Avila-Quintero VJ, Curlin K, Flores JM, Bloch MH. Sexual Orientation and Racial Bias in Relation to Medical Specialty. Journal Of Homosexuality 2022, 71: 574-599. PMID: 36269161, DOI: 10.1080/00918369.2022.2132441.Peer-Reviewed Original ResearchTeen Advisory Council Survey's Factors Associated With Self-Harming Thoughts
McPherson P, Alderman L, Temple J, Lawrence R, Avila-Quintero V, Magner J, Sagrera C, Patterson J, Murnane K. Teen Advisory Council Survey's Factors Associated With Self-Harming Thoughts. Frontiers In Psychiatry 2022, 13: 851477. PMID: 35815025, PMCID: PMC9259897, DOI: 10.3389/fpsyt.2022.851477.Peer-Reviewed Original ResearchSelf-harm thoughtsLife stressorsHigh-stakes tasksMental health professionalsHigh school studentsIdentification of stressorsLived experienceCommon stressorsGen Z studentsStressorsPeersSchool studentsTeensSuicide preventionAdolescentsThoughtStudentsHealth professionalsExperienceSchool systemSchoolsProfessionalsSuicideAction itemsLocal school systemDoes the SDMQ-9 Predict Changes in HbA1c Levels? An Ecuadorian Cohort
Bajaña M, Moncayo-Rizzo J, Alvarado-Villa G, Avila-Quintero V. Does the SDMQ-9 Predict Changes in HbA1c Levels? An Ecuadorian Cohort. Medicina 2022, 58: 380. PMID: 35334556, PMCID: PMC8950991, DOI: 10.3390/medicina58030380.Peer-Reviewed Original ResearchConceptsShared-decision makingWorse diabetic controlBody mass indexMajor health problemEcuadorian cohortEndocrinology outpatientsDiabetic controlMass indexTreatment adherencePatient controlsHealth problemsHealth statusElevated levelsSpecific populationsSignificant predictorsHbA1cDiabetesPatientsEducational levelPredict changesPredictorsMore investigationSample sizeHigh levelsLinear regressionCharacteristics of Assaultive Patients Whom Inpatient Psychiatric Staff Report to Law Enforcement
Chaffkin J, Barnes TA, Avila Quintero VJ, Flores JM, Lin E, Wasser T. Characteristics of Assaultive Patients Whom Inpatient Psychiatric Staff Report to Law Enforcement. Psychiatric Services 2022, 73: 768-773. PMID: 35172591, DOI: 10.1176/appi.ps.202100140.Peer-Reviewed Original ResearchConceptsInpatient psychiatric unitPsychiatric unitChronic mental illnessDegree of injuryClinical factorsRegression modelsCertain patientsCriminal justice involvementPsychotic symptomsAssaultive patientsPatient assaultsPatient encountersMental illnessPatientsHospital systemLarger quantitative studyPredictive variablesStaff reportsJustice involvementDescriptive statisticsStaffStaff decisionsMedicationsAdmissionInjurySurgical repair of nasal septal perforations: A systematic review and meta‐analysis
Fermin J, Bui R, McCoul E, Alt J, Avila‐Quintero V, Chang B, Yim M. Surgical repair of nasal septal perforations: A systematic review and meta‐analysis. International Forum Of Allergy & Rhinology 2022, 12: 1104-1119. PMID: 34978162, DOI: 10.1002/alr.22965.Peer-Reviewed Original ResearchConceptsNasal septal perforationEndonasal approachSurgical managementSurgical repairSeptal perforationSuccess rateElectronic database searchCINAHL Plus databasesMedian MINORS scoreRandom-effects modelUse of graftsEnglish-language studiesNSP repairPooled proportionInterposition graftMethodological IndexStudy criteriaPrimary diagnosisSurgical approachMINORS scoreInclusion criteriaOutcome measuresUnilateral flapModerate heterogeneityBilateral flapsThe effects of stimulant dose and dosing strategy on treatment outcomes in attention-deficit/hyperactivity disorder in children and adolescents: a meta-analysis
Farhat LC, Flores JM, Behling E, Avila-Quintero VJ, Lombroso A, Cortese S, Polanczyk GV, Bloch MH. The effects of stimulant dose and dosing strategy on treatment outcomes in attention-deficit/hyperactivity disorder in children and adolescents: a meta-analysis. Molecular Psychiatry 2022, 27: 1562-1572. PMID: 35027679, DOI: 10.1038/s41380-021-01391-9.Peer-Reviewed Original ResearchConceptsFixed-dose trialAttention-deficit/hyperactivity disorderDose-limiting adverse eventsChildren/adolescentsAdverse eventsFlexible-dose trialTerms of efficacyClinical practiceHigh dosesFlexible dose designIntolerable adverse eventsHyperactivity disorderIncremental benefitLikelihood of discontinuationADHD symptomsLarge systematic reviewSchool-aged children/adolescentsFlexible titrationPotential long-term effectsSymptom controlTreatment discontinuationClinical outcomesStimulant dosesDaily dosesClinical guidelines
2021
Pharmacological and somatic treatment effects on suicide in adults: A systematic review and meta‐analysis
Wilkinson ST, Diaz D, Rupp ZW, Kidambi A, Ramirez KL, Flores JM, Avila‐Quintero V, Rhee TG, Olfson M, Bloch MH. Pharmacological and somatic treatment effects on suicide in adults: A systematic review and meta‐analysis. Depression And Anxiety 2021, 39: 100-112. PMID: 34762330, DOI: 10.1002/da.23222.Peer-Reviewed Original ResearchConceptsOdds of suicidePlacebo/Suicide riskPsychotic disordersBipolar disorderSystematic reviewSuicide deathsMeta-analyzed associationsNon-clozapine antipsychoticsMagnetic seizure therapySomatic interventionsVagus nerve stimulationNewcastle-Ottawa ScaleAntiepileptic mood stabilizersTranscranial magnetic stimulationCertain clinical contextsDirect current stimulationEffects of pharmacologicPublic health crisisSeizure therapyElectroconvulsive therapyNerve stimulationMood stabilizersStudy qualityProtective effectOUTCOMES FOR BLACK AND HISPANIC PATIENTS WITH COVID-19: A LARGE HEALTHCARE SYSTEM EXPERIENCE
Anirudh R, Alnababteh M, Flores J, Avila-Quintero V, Laing N, Groninger H, Zaaqoq A. OUTCOMES FOR BLACK AND HISPANIC PATIENTS WITH COVID-19: A LARGE HEALTHCARE SYSTEM EXPERIENCE. CHEST Journal 2021, 160: a581. PMCID: PMC8503149, DOI: 10.1016/j.chest.2021.07.559.Peer-Reviewed Original ResearchOpioid-induced analgesia among persons with opioid use disorder receiving methadone or buprenorphine: A systematic review of experimental pain studies
De Aquino JP, Parida S, Avila-Quintero VJ, Flores J, Compton P, Hickey T, Gómez O, Sofuoglu M. Opioid-induced analgesia among persons with opioid use disorder receiving methadone or buprenorphine: A systematic review of experimental pain studies. Drug And Alcohol Dependence 2021, 228: 109097. PMID: 34601272, PMCID: PMC8595687, DOI: 10.1016/j.drugalcdep.2021.109097.Peer-Reviewed Original ResearchConceptsOpioid agonist therapyOpioid use disorderExperimental pain studiesAbuse potentialRespiratory depressionAcute painPain studiesUse disordersSystematic reviewGreater abuse potentialHigh-potency opioidsMethadone-maintained personsSignificant pain reliefRespiratory depressant effectsHigh-potency compoundsOpioid naïveAgonist therapyOpioid dosesPain reliefAnalgesic effectSevere painDepressant effectAdditional dosesStudy qualityHealthy personsParental Age and the Risk for Alzheimer’s Disease in Offspring: Systematic Review and Meta-Analysis
Szejko N, Macul Ferreira de Barros P, Avila-Quintero VJ, Lombroso A, Bloch MH. Parental Age and the Risk for Alzheimer’s Disease in Offspring: Systematic Review and Meta-Analysis. Dementia And Geriatric Cognitive Disorders Extra 2021, 11: 140-150. PMID: 34178019, PMCID: PMC8216010, DOI: 10.1159/000515523.Peer-Reviewed Original ResearchAlzheimer's diseaseSystematic reviewParental ageRisk factorsPaternal ageRisk of ADLate Alzheimer's diseaseAdequate control groupsCohort studyPotential confoundersCommon causeCase controlControl groupElectronic databasesMeta-AnalysisVersion 16Significant associationDown syndromeDifferential riskDiseaseRelevant studiesAgeOlder parentsRiskMethodological limitationsDeficits in hippocampal-dependent memory across different rodent models of early life stress: systematic review and meta-analysis
Rocha M, Wang D, Avila-Quintero V, Bloch MH, Kaffman A. Deficits in hippocampal-dependent memory across different rodent models of early life stress: systematic review and meta-analysis. Translational Psychiatry 2021, 11: 231. PMID: 33879774, PMCID: PMC8058062, DOI: 10.1038/s41398-021-01352-4.Peer-Reviewed Original ResearchConceptsEarly life stressNovel object recognitionMorris water mazeDifferent rodent modelsContextual fear conditioningMaternal separationHippocampal-dependent memoryVentral hippocampusDorsal hippocampusRodent modelsLife stressAbnormal hippocampal developmentStandardized mean differenceSimilar cognitive deficitsWeb of ScienceModerate effect sizeCFC taskFunctional deficitsFear conditioningInclusion criteriaPreclinical studiesReduced freezingHippocampal developmentLimited beddingWater mazeCorrection to: Racial Implicit Associations in Psychiatric Diagnosis, Treatment, and Compliance Expectations
Londono Tobon A, Flores JM, Taylor JH, Johnson I, Landeros-Weisenberger A, Aboiralor O, Avila-Quintero VJ, Bloch MH. Correction to: Racial Implicit Associations in Psychiatric Diagnosis, Treatment, and Compliance Expectations. Academic Psychiatry 2021, 45: 533-534. PMID: 33821450, DOI: 10.1007/s40596-021-01435-w.Peer-Reviewed Original Research