cDNA cloning, chromosomal localization, and expression analysis of human BEHAB/brevican, a brain specific proteoglycan regulated during cortical development and in glioma
Gary S, Zerillo C, Chiang V, Gaw J, Gray G, Hockfield S. cDNA cloning, chromosomal localization, and expression analysis of human BEHAB/brevican, a brain specific proteoglycan regulated during cortical development and in glioma. Gene 2000, 256: 139-147. PMID: 11054543, DOI: 10.1016/s0378-1119(00)00362-0.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceBase SequenceBrainBrevicanCarrier ProteinsCerebral CortexChondroitin Sulfate ProteoglycansChromosome MappingChromosomes, Human, Pair 1Cloning, MolecularDNA, ComplementaryGene ExpressionGene Expression Regulation, DevelopmentalGene Expression Regulation, NeoplasticGliomaHumansLectins, C-TypeMolecular Sequence DataNerve Tissue ProteinsProtein IsoformsProteoglycansRNATranscription, GeneticConceptsBEHAB/brevicanHuman gliomasChondroitin sulfate proteoglycanNormal adult cortexBrain-specific proteoglycanNormal human cortexBrain-specific memberAdult cortexCortical developmentRNase protection analysisGliomasHuman cortexNormal levelsBrain developmentLow levelsLectican familyExtracellular matrixBrevicanSpecific proteoglycansSulfate proteoglycanHuman brainCortexMiceFull-length isoformUniformly low level