2021
Reirradiation With Stereotactic Radiosurgery After Local or Marginal Recurrence of Brain Metastases From Previous Radiosurgery
Kowalchuk RO, Niranjan A, Lee CC, Yang HC, Liscak R, Guseynova K, Tripathi M, Kumar N, Peker S, Samanci Y, Hess J, Chiang V, Iorio-Morin C, Mathieu D, Pikis S, Wei Z, Lunsford LD, Trifiletti DM, Sheehan JP. Reirradiation With Stereotactic Radiosurgery After Local or Marginal Recurrence of Brain Metastases From Previous Radiosurgery. International Journal Of Radiation Oncology • Biology • Physics 2021, 112: 726-734. PMID: 34644606, DOI: 10.1016/j.ijrobp.2021.10.008.Peer-Reviewed Original ResearchConceptsLocal tumor controlRepeat stereotactic radiosurgeryRadiation necrosisStereotactic radiosurgeryBrain metastasesTumor controlMaximum doseMarginal recurrenceBiopsy-proven non-small cell lung cancerIsodose lineNon-small cell lung cancerRisk of RNPreoperative stereotactic radiosurgeryPrior stereotactic radiosurgerySymptomatic radiation necrosisNeuro-Oncology criteriaCell lung cancerPrescription isodose linePrevious radiosurgeryMargin dosePrimary endpointPrior immunotherapyLung cancerMajor indicationTumor volume
2019
RADI-34. USE OF LOW-DOSE STEREOTACTIC RADIOSURGERY FOR ADVANCED BRAIN METASTASES
Yang D, Yu J, Chiang V. RADI-34. USE OF LOW-DOSE STEREOTACTIC RADIOSURGERY FOR ADVANCED BRAIN METASTASES. Neuro-Oncology Advances 2019, 1: i28-i28. PMCID: PMC7213353, DOI: 10.1093/noajnl/vdz014.126.Peer-Reviewed Original ResearchGamma Knife stereotactic radiosurgeryBrain metastasesStereotactic radiosurgeryOverall survivalDisease progressionTime to disease progressionBRAF V600E tumorsMutation-targeted therapiesMedian overall survivalMetastatic melanoma patientsTreat brain metastasesPoor performance statusTumor controlMelanoma patientsSystemic therapyAdvanced diseasePerformance statusRe-treatmentTesticular cancerComposite endpointMetastasisSystemic agentsStudy exitImmunotherapyPatients
2015
Post-radiosurgical edema associated with parasagittal and parafalcine meningiomas: a multicenter study
Sheehan JP, Cohen-Inbar O, Ruangkanchanasetr R, Bulent Omay S, Hess J, Chiang V, Iorio-Morin C, Alonso-Basanta M, Mathieu D, Grills IS, Lee JY, Lee CC, Dade Lunsford L. Post-radiosurgical edema associated with parasagittal and parafalcine meningiomas: a multicenter study. Journal Of Neuro-Oncology 2015, 125: 317-324. PMID: 26329323, DOI: 10.1007/s11060-015-1911-1.Peer-Reviewed Original ResearchConceptsStereotactic radiosurgeryParafalcine meningiomaTumor controlTumor volumeInternational Gamma Knife Research FoundationPost-surgical residual tumorAdjuvant stereotactic radiosurgeryRetrospective multicenter reviewTumor volume controlUpfront stereotactic radiosurgeryVenous sinus compressionMedian marginal doseMedian tumor volumeSubset of patientsLong-term followPeri-tumoral edemaExtent of edemaVenous sinus invasionMedian followMarginal doseMulticenter reviewPrognostic factorsSinus compressionResidual tumorMulticenter studyEvolution of multidisciplinary brain metastasis management: case study and literature review.
Colaco R, Martin P, Chiang V. Evolution of multidisciplinary brain metastasis management: case study and literature review. The Yale Journal Of Biology And Medicine 2015, 88: 157-65. PMID: 26029014, PMCID: PMC4445437.Peer-Reviewed Original ResearchConceptsBrain metastasesManagement of BMProgression-free survivalLocal tumor controlLong-term survivorsNeurocognitive side effectsBrain metastasis managementSymptom reliefTumor burdenTumor controlCancer patientsTreatment modalitiesMetastasis managementSide effectsRadiation modalitiesFunctional independenceContemporary managementPatientsLiterature reviewSurvivalModalitiesOverall qualityCoordinated approachManagementPrognosisGamma Knife radiosurgery for facial nerve schwannomas: a multicenter study.
Sheehan JP, Kano H, Xu Z, Chiang V, Mathieu D, Chao S, Akpinar B, Lee JY, Yu JB, Hess J, Wu HM, Chung WY, Pierce J, Missios S, Kondziolka D, Alonso-Basanta M, Barnett GH, Lunsford LD. Gamma Knife radiosurgery for facial nerve schwannomas: a multicenter study. Journal Of Neurosurgery 2015, 123: 387-94. PMID: 25955875, DOI: 10.3171/2014.11.jns141160.Peer-Reviewed Original ResearchConceptsFacial nerve schwannomaFacial nerve functionNorth American Gamma Knife ConsortiumHouse-Brackmann scoreStereotactic radiosurgeryNerve functionTumor controlNeurological preservationMargin doseMedian ageNerve schwannomaPreoperative facial nerve functionNormal facial nerve functionResidual/recurrent tumorActuarial tumor controlEffective salvage treatmentMean margin dosePermanent neurological symptomsTumor margin doseUpfront stereotactic radiosurgeryPatients' median ageMean tumor volumeTreatment of choiceGamma knife radiosurgeryRare intracranial tumorsGamma Knife radiosurgery for posterior fossa meningiomas: a multicenter study.
Sheehan JP, Starke RM, Kano H, Barnett GH, Mathieu D, Chiang V, Yu JB, Hess J, McBride HL, Honea N, Nakaji P, Lee JY, Rahmathulla G, Evanoff WA, Alonso-Basanta M, Lunsford LD. Gamma Knife radiosurgery for posterior fossa meningiomas: a multicenter study. Journal Of Neurosurgery 2015, 122: 1479-89. PMID: 25859812, DOI: 10.3171/2014.10.jns14139.Peer-Reviewed Original ResearchConceptsPosterior fossa meningiomasTumor volumeStereotactic radiosurgeryTumor controlRadiation therapyNorth American Gamma Knife ConsortiumTumor progressionActuarial tumor controlMedian margin doseMedian patient agePrior radiation therapyMean tumor volumeGamma knife radiosurgerySmaller tumor volumeNeurological preservationMargin dosePrior resectionClinical stabilityNeurological declinePatient ageShunt placementRecurrent tumorsClinical entityMulticenter studyKnife radiosurgery
2014
Stereotactic radiosurgery of petroclival meningiomas: a multicenter study
Starke R, Kano H, Ding D, Nakaji P, Barnett GH, Mathieu D, Chiang V, Yu JB, Hess J, McBride HL, Honea N, Lee JY, Rahmathulla G, Evanoff WA, Alonso-Basanta M, Lunsford LD, Sheehan JP. Stereotactic radiosurgery of petroclival meningiomas: a multicenter study. Journal Of Neuro-Oncology 2014, 119: 169-176. PMID: 24821284, DOI: 10.1007/s11060-014-1470-x.Peer-Reviewed Original ResearchConceptsGamma knife radiosurgeryPetroclival meningiomasMulticenter studyFavorable outcomeTumor volumeActuarial progression-free survival ratesNorth American Gamma Knife ConsortiumProgression-free survival ratesFree survival ratePrimary treatment modalityProgression of symptomsSmaller tumor volumeComplete microsurgical resectionNeurological preservationUpfront radiosurgeryPrior radiotherapyMost patientsMicrosurgical resectionSignificant morbidityNeurological functionMaximal doseTumor controlTreatment modalitiesKnife radiosurgeryFemale genderGamma Knife radiosurgery for sellar and parasellar meningiomas: a multicenter study.
Sheehan JP, Starke RM, Kano H, Kaufmann AM, Mathieu D, Zeiler FA, West M, Chao ST, Varma G, Chiang VL, Yu JB, McBride HL, Nakaji P, Youssef E, Honea N, Rush S, Kondziolka D, Lee JY, Bailey RL, Kunwar S, Petti P, Lunsford LD. Gamma Knife radiosurgery for sellar and parasellar meningiomas: a multicenter study. Journal Of Neurosurgery 2014, 120: 1268-77. PMID: 24678777, DOI: 10.3171/2014.2.jns13139.Peer-Reviewed Original ResearchConceptsGamma knife radiosurgeryPrior radiation therapyParasellar meningiomasSellar meningiomasKnife radiosurgeryRadiation therapyPrior surgeryMulticenter studyTumor controlTumor volumeActuarial progression-free survival ratesNorth American Gamma Knife ConsortiumTumor progressionProgression-free survival ratesCox multivariate regression analysisTumor margin doseNew neurological deficitsCranial nerve deficitsPrimary treatment modalityKaplan-Meier analysisCranial nerves VLarger tumor volumeConventional radiation therapyMonths of imagingMultivariate regression analysis
2013
Gamma Knife radiosurgery for the management of nonfunctioning pituitary adenomas: a multicenter study.
Sheehan JP, Starke RM, Mathieu D, Young B, Sneed PK, Chiang VL, Lee JY, Kano H, Park KJ, Niranjan A, Kondziolka D, Barnett GH, Rush S, Golfinos JG, Lunsford LD. Gamma Knife radiosurgery for the management of nonfunctioning pituitary adenomas: a multicenter study. Journal Of Neurosurgery 2013, 119: 446-56. PMID: 23621595, DOI: 10.3171/2013.3.jns12766.Peer-Reviewed Original ResearchConceptsPrior radiation therapyPituitary adenomasTumor controlNonfunctional pituitary adenomasNerve dysfunctionRadiation therapyNorth American Gamma Knife ConsortiumActuarial tumor controlDegree of hypopituitarismMulticenter patient populationTime of radiosurgeryCranial nerve deficitsPercent of patientsCranial nerve functionOptic nerve dysfunctionCranial nerve dysfunctionGamma Knife surgeryManagement of patientsOverall tumor controlGamma knife radiosurgeryExternal beam radiotherapyProgressive cranial nerve deficitsCommon intracranial neoplasmsDelayed hypopituitarismMargin doses
2011
Stereotactic radiosurgery with or without whole-brain radiotherapy for brain metastases: an update
Park HS, Chiang VL, Knisely JP, Raldow AC, Yu JB. Stereotactic radiosurgery with or without whole-brain radiotherapy for brain metastases: an update. Expert Review Of Anticancer Therapy 2011, 11: 1731-1738. PMID: 22050022, DOI: 10.1586/era.11.165.Peer-Reviewed Original ResearchConceptsWhole-brain radiation therapyStereotactic radiosurgeryBrain metastasesAddition of SRSUse of SRSMD Anderson Cancer CenterWhole brain radiotherapyLocal tumor controlStandard of careAnderson Cancer CenterNormal brain tissueNonrandomized evidenceLimited metastasesOligometastatic diseaseCancer CenterTumor controlRelative sparingRadiation therapyBrain tissueMetastasisSingle fractionNormal tissuesPatientsRadiosurgeryTrials