Upfront Magnetic Resonance Imaging-Guided Stereotactic Laser-Ablation in Newly Diagnosed Glioblastoma: A Multicenter Review of Survival Outcomes Compared to a Matched Cohort of Biopsy-Only Patients.
Mohammadi AM, Sharma M, Beaumont TL, Juarez KO, Kemeny H, Dechant C, Seas A, Sarmey N, Lee BS, Jia X, Fecci PE, Baehring J, Moliterno J, Chiang VL, Ahluwalia MS, Kim AH, Barnett GH, Leuthardt EC. Upfront Magnetic Resonance Imaging-Guided Stereotactic Laser-Ablation in Newly Diagnosed Glioblastoma: A Multicenter Review of Survival Outcomes Compared to a Matched Cohort of Biopsy-Only Patients. Neurosurgery 2018, 85: 762-772. PMID: 30476325, PMCID: PMC7054708, DOI: 10.1093/neuros/nyy449.Peer-Reviewed Original ResearchConceptsProgression-free survivalDisease-specific deathOverall survivalChemo/radiotherapyPrognostic groupsOnly cohortNGBM patientsSpecific deathTumor volumeBiopsy-only patientsMedian tumor volumeFavorable prognostic factorRadiation/chemotherapyEffective treatment modalityStereotactic laser ablationMagnetic resonance imagingLA cohortMatched CohortMulticenter reviewPrognostic factorsUpfront treatmentIndependent predictorsSurvival outcomesTreatment modalitiesTumor location