2021
Incidence and characteristics of metastatic intracranial lesions in stage III and IV melanoma: a single institute retrospective analysis
Sandhu MRS, Chiang VL, Tran T, Yu JB, Weiss S, Goldberg S, Aboian M, Kluger HM, Mahajan A. Incidence and characteristics of metastatic intracranial lesions in stage III and IV melanoma: a single institute retrospective analysis. Journal Of Neuro-Oncology 2021, 154: 197-203. PMID: 34351544, DOI: 10.1007/s11060-021-03813-8.Peer-Reviewed Original ResearchConceptsStage IV melanomaMetastatic brain lesionsStage IIIInitial diagnosisTumor RegistryOverall incidenceBrain lesionsBM incidenceSingle-institute retrospective analysisBM developmentBrain metastases incidenceIncidence of BMInstitution's tumor registryStage III patientsTime of diagnosisMetastatic intracranial lesionsCommon genetic mutationsTumor genetic profileGenetic profileBM occurrenceMedian durationAdvanced melanomaSurveillance regimenIII patientsMedian time
2020
Estrogen/progesterone receptor and HER2 discordance between primary tumor and brain metastases in breast cancer and its effect on treatment and survival.
Sperduto PW, Mesko S, Li J, Cagney D, Aizer A, Lin NU, Nesbit E, Kruser TJ, Chan J, Braunstein S, Lee J, Kirkpatrick JP, Breen W, Brown PD, Shi D, Shih HA, Soliman H, Sahgal A, Shanley R, Sperduto W, Lou E, Everett A, Boggs DH, Masucci L, Roberge D, Remick J, Plichta K, Buatti JM, Jain S, Gaspar LE, Wu CC, Wang TJC, Bryant J, Chuong M, Yu J, Chiang V, Nakano T, Aoyama H, Mehta MP. Estrogen/progesterone receptor and HER2 discordance between primary tumor and brain metastases in breast cancer and its effect on treatment and survival. Neuro-Oncology 2020, 22: 1359-1367. PMID: 32034917, PMCID: PMC7523450, DOI: 10.1093/neuonc/noaa025.Peer-Reviewed Original ResearchConceptsBreast cancer brain metastasesHuman epidermal growth factor receptor 2Primary tumorProgesterone receptorMedian survivalEstrogen receptorBrain metastasesDiscordance rateHER2-negative primary tumorsEstrogen/progesterone receptorsEpidermal growth factor receptor 2Time of metastasisCancer brain metastasesGrowth factor receptor 2Breast cancer treatmentIncidence of discordanceFactor receptor 2Subsequent treatmentBCBM patientsHER2 discordanceReceptor discordanceMost patientsReceptor statusInitial diagnosisHER2 status
2016
The Role of Laser-Induced Thermal Therapy in the Management of Malignant Gliomas
Fomchenko E, Chiang V. The Role of Laser-Induced Thermal Therapy in the Management of Malignant Gliomas. 2016, 103-119. DOI: 10.1007/978-3-319-49864-5_7.Peer-Reviewed Original ResearchLaser interstitial thermal therapyHigh-grade gliomasSurgical resectionUse of LITTCommon primary CNS malignancyRecurrent high-grade gliomaOverall treatment algorithmPrimary CNS malignanciesRole of LITTPoor surgical candidatesStandard surgical approachDe novo diagnosisDeep gray nucleiInterstitial thermal therapyLaser thermal ablationAggressive treatmentCNS malignanciesSurgical candidatesImproved survivalInitial diagnosisSignificant morbidityTreatment algorithmMulticenter studySurgical approachBasal ganglia
2013
Secondary Neoplasms After Stereotactic Radiosurgery
Patel TR, Chiang VL. Secondary Neoplasms After Stereotactic Radiosurgery. World Neurosurgery 2013, 81: 594-599. PMID: 24148883, DOI: 10.1016/j.wneu.2013.10.043.Peer-Reviewed Original ResearchConceptsStereotactic radiosurgerySecondary neoplasmsCentral nervous system diseaseLong-term surveillance imagingNervous system diseasesRadiation-induced neoplasmsLong-term riskInitial diagnosisSurveillance imagingVestibular schwannomaTreatment paradigmSubsequent riskSystem diseasesNeoplasmsMedical radiationRadiation exposureRadiosurgeryRiskPatientsSchwannomaYearsDiseaseDiagnosis