2021
Predictors of Population Awareness of Cancer Genetic Tests: Implications for Enhancing Equity in Engaging in Cancer Prevention and Precision Medicine.
Giri V, Shimada A, Leader A. Predictors of Population Awareness of Cancer Genetic Tests: Implications for Enhancing Equity in Engaging in Cancer Prevention and Precision Medicine. JCO Precision Oncology 2021, 5: 1699-1708. PMID: 34778693, PMCID: PMC8585288, DOI: 10.1200/po.21.00231.Peer-Reviewed Original ResearchConceptsExact testCancer informationMultivariate logistic regression modelPopulation-based studyCross-sectional studyFisher's exact testPopulation-based sampleGenetic awarenessNational Trends SurveyNon-Hispanic whitesLogistic regression modelsPrecision medicine eraMiddle-high incomeDiverse population-based sampleCancer careModifiable factorsPersonalized cancer treatmentCancer preventionFemale genderHealth literacyCancer fatalismMedical literacyMultivariate analysisEthnic disparitiesGenetic testingAdopting Consensus Terms for Testing in Precision Medicine
Martin N, Tepper J, Giri V, Stinchcombe T, Cheng H, Javle M, Konnick E. Adopting Consensus Terms for Testing in Precision Medicine. JCO Precision Oncology 2021, 5: 1563-1567. PMID: 34651094, PMCID: PMC8509918, DOI: 10.1200/po.21.00027.Peer-Reviewed Original ResearchConceptsGenetic testingTreatment decisionsOncology health care providersHealth care providersPrecision medicineLow socioeconomic statusPreferred termPatient advocacy groupsGermline testingTumor characteristicsOncology carePatient preferencesBiomarker testingPatient educationCancer riskCare providersPatient confusionSolid tumorsBlood cancersGermline mutationsGermline variantsAppropriate testingPatientsSocioeconomic statusGenomic testingGenetic Testing Guidelines and Education of Health Care Providers Involved in Prostate Cancer Care
Mark J, McDougall C, Giri V. Genetic Testing Guidelines and Education of Health Care Providers Involved in Prostate Cancer Care. Urologic Clinics Of North America 2021, 48: 311-322. PMID: 34210487, DOI: 10.1016/j.ucl.2021.03.003.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsGermline testingProstate cancerGenetic testing guidelinesFirst-line therapyCastration-resistant diseaseEarly-stage diseaseProstate cancer careHealth care providersGenetic test resultsPCA careCancer careCare providersScreening settingCancer implicationsPARP inhibitorsTesting guidelinesPossible roleDiseaseCareMenPractice strategiesOncologistsTestingTherapyCancer
2020
Practical Considerations and Challenges for Germline Genetic Testing in Patients With Prostate Cancer: Recommendations From the Germline Genetics Working Group of the PCCTC.
Szymaniak BM, Facchini LA, Giri VN, Antonarakis ES, Beer TM, Carlo MI, Danila DC, Dhawan M, George D, Graff JN, Gupta S, Heath E, Higano CS, Liu G, Molina AM, Paller CJ, Patnaik A, Petrylak DP, Reichert Z, Rettig MB, Ryan CJ, Taplin ME, Vinson J, Whang YE, Morgans AK, Cheng HH, McKay RR. Practical Considerations and Challenges for Germline Genetic Testing in Patients With Prostate Cancer: Recommendations From the Germline Genetics Working Group of the PCCTC. JCO Oncology Practice 2020, 16: 811-819. PMID: 32986533, PMCID: PMC7735040, DOI: 10.1200/op.20.00431.Peer-Reviewed Original ResearchMeSH KeywordsGenetic TestingGerm CellsGerm-Line MutationHumansMalePrecision MedicineProstatic NeoplasmsConceptsGermline genetic testingProstate cancerGenetic testingNumber of patientsCritical unmet needCurrent guidelinesTesting deliveryPatientsUnmet needPrecision oncologyGenomic testingGenetic counselingGenetics providersGenetic servicesClinical workflowCancerOncologyLimited accessWorking GroupGuidelinesStandardized systemProvidersTestingClinic
2019
Germline Genetic Testing in Advanced Prostate Cancer; Practices and Barriers: Survey Results from the Germline Genetics Working Group of the Prostate Cancer Clinical Trials Consortium
Paller CJ, Antonarakis ES, Beer TM, Borno HT, Carlo MI, George DJ, Graff JN, Gupta S, Heath EI, Higano CS, McKay RR, Morgans AK, Patnaik A, Petrylak DP, Rettig MB, Ryan CJ, Taplin ME, Whang YE, Vinson J, Cheng HH, Giri VN, Group P. Germline Genetic Testing in Advanced Prostate Cancer; Practices and Barriers: Survey Results from the Germline Genetics Working Group of the Prostate Cancer Clinical Trials Consortium. Clinical Genitourinary Cancer 2019, 17: 275-282.e1. PMID: 31171481, PMCID: PMC6662206, DOI: 10.1016/j.clgc.2019.04.013.Peer-Reviewed Original ResearchConceptsProstate Cancer Clinical Trials ConsortiumGermline genetic testingClinical Trials ConsortiumGenetic testingPCa patientsAdvanced prostate cancer patientsAdvanced prostate cancerMetastatic PCa patientsClinical trial eligibilityProstate cancer patientsPan-cancer panelCancer gene panelTrial eligibilityChoice of assayLocal diseaseCancer CenterAcademic oncologistsCancer patientsProstate cancerCancer treatment facilitiesPatientsBusy clinicPrecision therapyPersonalized treatmentWorking GroupGermline Testing for Men With Prostate Cancer: Navigating an Expanding New World of Genetic Evaluation for Precision Therapy and Precision Management
Giri V, Hyatt C, Gomella L. Germline Testing for Men With Prostate Cancer: Navigating an Expanding New World of Genetic Evaluation for Precision Therapy and Precision Management. Journal Of Clinical Oncology 2019, 37: jco.18.02181. PMID: 30978156, DOI: 10.1200/jco.18.02181.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2017
The Role of Genetic Counseling in Familial and Sporadic Cancer: Considerations, Challenges, and Collaboration.
Giri V, Yurgelun M, Robson M. The Role of Genetic Counseling in Familial and Sporadic Cancer: Considerations, Challenges, and Collaboration. Annals Of Internal Medicine 2017, 167: 884-885. PMID: 29086794, DOI: 10.7326/m17-2512.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements