2020
The effect of neighborhood social environment on prostate cancer development in black and white men at high risk for prostate cancer
Lynch S, Handorf E, Sorice K, Blackman E, Bealin L, Giri V, Obeid E, Ragin C, Daly M. The effect of neighborhood social environment on prostate cancer development in black and white men at high risk for prostate cancer. PLOS ONE 2020, 15: e0237332. PMID: 32790761, PMCID: PMC7425919, DOI: 10.1371/journal.pone.0237332.Peer-Reviewed Original ResearchConceptsProstate-specific antigenPCa family historyHigh-risk menProbability of PCaFamily historyPCa diagnosisRisk menWhite menDigital rectal examEarly Detection ProgramClinical risk assessmentProstate cancer disparitiesProstate cancer developmentPatient risk assessmentNeighborhood socioeconomic factorsPatient-level modelsCox regressionRectal examBaseline ageCancer disparitiesPatient variablesProstate cancerHigh riskNeighborhood social environmentClinical relevance
2017
Prevalence and Characteristics of Patients with Suspected Inherited Renal Cell Cancer: Application of the ACMG/NSGC Genetic Referral Guidelines to Patient Cohorts
Truong H, Hegarty S, Gomella L, Kelly W, Trabulsi E, Lallas C, Giri V. Prevalence and Characteristics of Patients with Suspected Inherited Renal Cell Cancer: Application of the ACMG/NSGC Genetic Referral Guidelines to Patient Cohorts. Journal Of Genetic Counseling 2017, 26: 548-555. PMID: 28101821, DOI: 10.1007/s10897-016-0020-4.Peer-Reviewed Original ResearchConceptsRenal cell cancerReferral criteriaCell cancerReferral guidelinesDiagnosis of RCCConsensus criteriaInstitutional cancer registryCharacteristics of patientsReferral of patientsGenetic counselingChi-square testRate of whitesCross-sectional analysisCancer risk managementHereditary renal cell cancerSEER cohortWhite patientsBlack patientsInstitutional cohortRCC syndromesCancer RegistryPatient cohortKidney cancerAmerican CollegePatients
2013
Validation of association of genetic variants at 10q with prostate‐specific antigen (PSA) levels in men at high risk for prostate cancer
Chang B, Hughes L, Chen D, Gross L, Ruth K, Giri V. Validation of association of genetic variants at 10q with prostate‐specific antigen (PSA) levels in men at high risk for prostate cancer. BJU International 2013, 113: e150-e156. PMID: 23937305, PMCID: PMC3830710, DOI: 10.1111/bju.12264.Peer-Reviewed Original ResearchConceptsProstate Cancer Risk Assessment ProgramHigh-risk groupPSA levelsCaucasian manProstate cancerFamily historyProstate cancer screening strategiesProstate cancer screening studyCancer Risk Assessment ProgramBaseline PSA levelsTaqMan single nucleotide polymorphismCancer screening strategiesCancer screening studySingle nucleotide polymorphismsAfrican American ethnicityAllele carrier statusBRCA gene mutationsPotential confoundersAge 35Eligibility criteriaClinical relevanceT alleleRisk assessment programA alleleCarrier status
2011
Rates and predictors of colorectal cancer screening by race among motivated men participating in a prostate cancer risk assessment program
Hall M, Ruth K, Giri V. Rates and predictors of colorectal cancer screening by race among motivated men participating in a prostate cancer risk assessment program. Cancer 2011, 118: 478-484. PMID: 21751189, PMCID: PMC3195866, DOI: 10.1002/cncr.26315.Peer-Reviewed Original ResearchConceptsProstate Cancer Risk Assessment ProgramCancer Risk Assessment ProgramAfrican American menUptake of CRCPredictors of uptakeCRC screeningLower endoscopyRisk assessment programAmerican menProstate cancerFamily historyFecal occult blood testingFecal occult blood testFox Chase Cancer CenterOccult blood testingColorectal cancer mortalityOccult blood testColorectal cancer screeningMultivariate logistic regressionProstate cancer clinicBlood testsBlood testingCancer CenterCancer mortalityCancer screening
2003
Genome‐wide scan for prostate cancer susceptibility genes using families from the University of Michigan prostate cancer genetics project finds evidence for linkage on chromosome 17 near BRCA1
Lange E, Gillanders E, Davis C, Brown W, Campbell J, Jones M, Gildea D, Riedesel E, Albertus J, Freas‐Lutz D, Markey C, Giri V, Dimmer J, Montie J, Trent J, Cooney K. Genome‐wide scan for prostate cancer susceptibility genes using families from the University of Michigan prostate cancer genetics project finds evidence for linkage on chromosome 17 near BRCA1. The Prostate 2003, 57: 326-334. PMID: 14601029, DOI: 10.1002/pros.10307.Peer-Reviewed Original ResearchConceptsProstate cancer susceptibility genesCancer susceptibility genesSusceptibility genesCandidate genesGenome-wide scan dataGenome-wide analysisChromosome 17Michigan Prostate Cancer Genetics ProjectWhole-genome analysisCancer candidate genesProstate Cancer Genetics ProjectSubset of pedigreesStratified linkage analysesPrevious linkage studiesGenome analysisLinkage scanChromosome 1Genetic markersLinkage analysisAffected individualsGenesLinkage regionGenetics ProjectChromosome 17qProstate cancer families