2022
Guidelines on Germline Testing for Urologic Tumor Syndromes
Gomella P, Mark J, Giri V, Kelly W, Gomella L. Guidelines on Germline Testing for Urologic Tumor Syndromes. European Urology Focus 2022, 8: 670-673. PMID: 35803854, DOI: 10.1016/j.euf.2022.06.010.Peer-Reviewed Original ResearchConceptsGermline testingCurrent guidelinesTumor syndromeTreatment of patientsScreening of patientsAvailability of testingDifferent organ systemsGenitourinary cancersGenitourinary tractUrologic cancersTreatment decisionsPatientsOrgan systemsGene mutationsCancerGenetic mutationsSyndromeFamily membersTreatmentGuidelinesMutationsTestingUse of geneticsTract
2020
Hereditary Prostate Cancer
Giri V, Beebe-Dimmer J, Cooney K. Hereditary Prostate Cancer. 2020, 283-292. DOI: 10.1201/9781351187435-33.Peer-Reviewed Original ResearchHereditary prostate cancerProstate cancerCancer syndromesGenetic testing guidelinesMetastatic prostate cancerProstate cancer riskOvarian cancer syndromeHereditary cancer syndromesPrecision oncology studyClinical featuresLynch syndromeFatal cancerCancer riskGenetic predispositionHereditary breastCancerGenetic testingFamilial clusteringTesting guidelinesSyndromeGermline geneticsOncology studiesCancer susceptibilityGermline variationClinical application
2019
Prevalence of Suspected Hereditary Cancer Syndromes and Germline Mutations Among a Diverse Cohort of Probands Reporting a Family History of Prostate Cancer: Toward Informing Cascade Testing for Men
Chandrasekar T, Gross L, Gomella L, Hegarty S, Leong J, Giri V. Prevalence of Suspected Hereditary Cancer Syndromes and Germline Mutations Among a Diverse Cohort of Probands Reporting a Family History of Prostate Cancer: Toward Informing Cascade Testing for Men. European Urology Oncology 2019, 3: 291-297. PMID: 31278035, DOI: 10.1016/j.euo.2019.06.010.Peer-Reviewed Original ResearchConceptsHereditary cancer syndromesProstate cancerCancer syndromesFamily historyGermline mutationsExact testHereditary breastGenetic testingAfrican AmericansPCa family historyAfrican American patientsOvarian cancer syndromeCascade genetic testingFisher's exact testHereditary prostate cancerBRCA mutationsLynch syndromeOvarian cancerSyndromeCancerCascade testingDiverse cohortAA participantsSpectrum of genesFHx
2016
HOXB13 and other high penetrant genes for prostate cancer
Pilie P, Giri V, Cooney K. HOXB13 and other high penetrant genes for prostate cancer. Asian Journal Of Andrology 2016, 18: 530-532. PMID: 27034017, PMCID: PMC4955175, DOI: 10.4103/1008-682x.175785.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsHereditary cancer syndromesMismatch repair genesCancer syndromesGermline mutationsProstate cancerMultiple primary malignanciesOvarian cancer syndromeCancer family syndromeDeleterious germline mutationsRare tumor typeCancer cell growthRepair genesHigh-penetrance genesPenetrant germline mutationsPrimary malignancyCommon cancerLi-FraumeniKey tumor suppressor genesFamily syndromeCancer tissuesHereditary breastTumor typesSyndromeCancer typesCancerPD13-07 CHARACTERIZATION OF UPPER TRACT UROTHELIAL CARCINOMA IN PATIENTS WITH CLINICAL SUSPICION OF LYNCH SYNDROME
Truong H, Hegarty S, Hubosky S, Healy K, Hoffman-Censits J, Giri V. PD13-07 CHARACTERIZATION OF UPPER TRACT UROTHELIAL CARCINOMA IN PATIENTS WITH CLINICAL SUSPICION OF LYNCH SYNDROME. Journal Of Urology 2016, 195: e300. DOI: 10.1016/j.juro.2016.02.978.Peer-Reviewed Original Research