2009
Massively parallel sequencing of the polyadenylated transcriptome of C. elegans
Hillier LW, Reinke V, Green P, Hirst M, Marra MA, Waterston RH. Massively parallel sequencing of the polyadenylated transcriptome of C. elegans. Genome Research 2009, 19: 657-666. PMID: 19181841, PMCID: PMC2665784, DOI: 10.1101/gr.088112.108.Peer-Reviewed Original ResearchConceptsTrans-spliced leader sequenceSplice junctionsParallel sequencingProtein-coding genesProtein-coding transcriptsPolyadenylated transcriptomeNoncoding transcriptsPutative genesNematode CaenorhabditisSomatic nucleiIntergenic regionGene setsLeader sequenceX chromosomeUnprecedented depthMost sequencesTranscriptsGenesMRNA levelsSequencingNotable regionNovel statistical approachAnnotationQuantitative natureSequence
2000
A Global Profile of Germline Gene Expression in C. elegans
Reinke V, Smith H, Nance J, Wang J, Van Doren C, Begley R, Jones S, Davis E, Scherer S, Ward S, Kim S. A Global Profile of Germline Gene Expression in C. elegans. Molecular Cell 2000, 6: 605-616. PMID: 11030340, DOI: 10.1016/s1097-2765(00)00059-9.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsArgonaute ProteinsCaenorhabditis elegansCaenorhabditis elegans ProteinsCell Cycle ProteinsCytoskeletal ProteinsDrosophila ProteinsGene Expression ProfilingGene Expression Regulation, DevelopmentalHelminth ProteinsMaleMembrane ProteinsOocytesProteinsReceptors, NotchRNA, MessengerRNA-Induced Silencing ComplexSpermatogenesisSpermatozoaX ChromosomeConceptsC. elegans germlineGermline gene expressionEmbryonic signaling pathwaysGene expression patternsStem cell proliferationChromosomal locationProtein kinaseX chromosomeDNA microarraysExpression patternsGene expressionSignaling pathwaysGermline transcriptsGenesCell proliferationGermlineGlobal profileTranscriptsChromosomesNew componentsKinaseMicroarrayPhosphatasePathwayOocytes