Regulatory analysis of the C. elegans genome with spatiotemporal resolution
Araya CL, Kawli T, Kundaje A, Jiang L, Wu B, Vafeados D, Terrell R, Weissdepp P, Gevirtzman L, Mace D, Niu W, Boyle AP, Xie D, Ma L, Murray JI, Reinke V, Waterston RH, Snyder M. Regulatory analysis of the C. elegans genome with spatiotemporal resolution. Nature 2014, 512: 400-405. PMID: 25164749, PMCID: PMC4530805, DOI: 10.1038/nature13497.Peer-Reviewed Original ResearchConceptsTranscription factorsRegulatory bindingMetazoan transcription factorsGlobal transcription factorTranscriptional regulatory eventsChIP-seq experimentsKey transcription factorFate specificationGenomic distributionC. elegansIndividual lineagesRegulatory circuitsGenomic coverageRegulatory eventsRegulatory underpinningsRegulatory proteinsBiological processesExpression dataCell typesShared patternRegulatory analysisBindingCaenorhabditisElegansGenome