Characterization of the distribution and dynamics of chromatin states in the C. elegans germ line reveals substantial H3K4me3 remodeling during oogenesis
Mazzetto M, Gonzalez L, Sanchez N, Reinke V. Characterization of the distribution and dynamics of chromatin states in the C. elegans germ line reveals substantial H3K4me3 remodeling during oogenesis. Genome Research 2023, 34: gr.278247.123. PMID: 38164610, PMCID: PMC10903938, DOI: 10.1101/gr.278247.123.Peer-Reviewed Original ResearchEpigenetic regulatory mechanismsGerm lineChromatin stateGerm cellsC. elegans germ lineGene expressionRegulatory mechanismsDevelopmental transitionsActive histone modification H3K4me3Most genomic studiesZygotic genome activationSmall RNA pathwaysSpatio-temporal expression patternsHistone modifications H3K4me3Chromatin accessibility dataGerm cell differentiationOverall transcript abundanceUndifferentiated germ cellsGenome activationRNA pathwaysChromatin landscapeChromatin organizationChromatin structureEssential genesHistone modifications