2024
Regional European genetic ancestry predicts type I interferon level and risk of severe viral infection
Nln I, Shum J, Ghodke-Puranik Y, Tipon R, Triese D, Amin S, Makol A, Osborn T, Chowdhary V, Thanarajasingam U, Muskardin T, Oke V, Gunnarsson I, Zickert A, Zervou M, Boumpas D, Svenungsson E, Goulielmos G, Niewold T. Regional European genetic ancestry predicts type I interferon level and risk of severe viral infection. QJM 2024, 117: 581-588. PMID: 38530799, PMCID: PMC11389909, DOI: 10.1093/qjmed/hcae052.Peer-Reviewed Original ResearchType I IFN levelsViral infection outcomesI interferonLupus patientsEuropean genetic ancestryInfection outcomesAnti-viral cytokinesSevere viral infectionsType I interferon levelsHost genetic factorsRisk of severe viral infectionsSevere organ failureI interferon levelsType I IFNType I interferonVirus prior to infectionViral hepatitisOrgan failureGenetic testingViral infectionI IFNOutcome dataHost defenseGenetic factorsGenetic ancestry
2018
TD-08 High type I interferon activity is associated with active class III/IV lupus nephritis in european-american lupus patients independent of anti-dsDNA antibodies
Iwamoto T, Dorschner J, Jensen M, Vsetecka D, Amin S, Makol A, Ernste F, Osborn T, Moder K, Chowdhary V, Niewold T. TD-08 High type I interferon activity is associated with active class III/IV lupus nephritis in european-american lupus patients independent of anti-dsDNA antibodies. 2018, a75.2-a76. DOI: 10.1136/lupus-2018-lsm.127.Peer-Reviewed Original ResearchPS1:1 High type i interferon activity is associated with active class 3/4 lupus nephritis in european-american lupus patients independent of anti-dsdna antibodies
Iwamoto T, Dorschner J, Jensen M, Vsetecka D, Amin S, Makol A, Ernste F, Osborn T, Moder K, Chowdhary V, Niewold T. PS1:1 High type i interferon activity is associated with active class 3/4 lupus nephritis in european-american lupus patients independent of anti-dsdna antibodies. 2018, a32.1-a32. DOI: 10.1136/lupus-2018-abstract.50.Peer-Reviewed Original Research