2016
GG-06 Single cell gene expression studies in lupus patient monocytes reveal novel patterns reflecting disease activity, interferon, and medical treatment
Jin Z, Fan W, Jensen M, Dorschner J, Vsetecka D, Amin S, Makol A, Ernste F, Osborn T, Moder K, Chowdhary V, Niewold T. GG-06 Single cell gene expression studies in lupus patient monocytes reveal novel patterns reflecting disease activity, interferon, and medical treatment. Lupus Science & Medicine 2016, 3: a30. DOI: 10.1136/lupus-2016-000179.58.Peer-Reviewed Original ResearchNon-classical monocytesSLE patientsDisease activityClassical monocytesPatients' monocytesCell gene expressionAnti-dsDNA titersHigh disease activityHigher IFN scoresSLE patient groupAnti-inflammatory genesMonocyte gene expressionPrednisone useGene expressionMedication useClinical featuresInterferon signatureC3 complementIFN scorePatient groupImmunologic characteristicsUnsupervised hierarchical clusteringMedical treatmentPatients
2002
Outcome in juvenile dermatomyositis.
Chowdhary V, Wakhlu A, Agarwal A, Misra R. Outcome in juvenile dermatomyositis. Indian Pediatrics 2002, 39: 931-5. PMID: 12428038.Peer-Reviewed Original ResearchConceptsJuvenile dermatomyositisComplete remissionMuscle involvementMuscle weaknessNeck muscle weaknessPharyngeal muscle involvementRespiratory muscle involvementTertiary care hospitalProximal muscle weaknessInterstitial lung diseaseGI bleedHeliotrope rashPartial remissionMedian durationCare hospitalMedian ageClinical featuresPyogenic infectionsLung diseaseRetrospective analysisPatientsCase recordsDermatomyositisRemissionComplications