1991
Lipid peroxidation and antielastase activity in the lung under oxidant stress: role of antioxidant defenses
Mohsenin V. Lipid peroxidation and antielastase activity in the lung under oxidant stress: role of antioxidant defenses. Journal Of Applied Physiology 1991, 70: 1456-1462. PMID: 2055821, DOI: 10.1152/jappl.1991.70.4.1456.Peer-Reviewed Original ResearchConceptsElastase inhibitory capacityAlveolar lining fluidLipid peroxidation productsLining fluidLavage fluidVitamin-supplemented groupOxidant stressLipid peroxidationPeroxidation productsControl groupLower respiratory tract fluidFour-week supplementationVitamin CRespiratory tract fluidNO2 exposureInactivation of alphaConjugated dienesVitamin supplementationNormal subjectsAntielastase activityInhibitory capacityOxidant exposureSignificant decreaseAntioxidant defensePeroxidation
1989
Oxidation of alpha 1-protease inhibitor: role of lipid peroxidation products
Mohsenin V, Gee J. Oxidation of alpha 1-protease inhibitor: role of lipid peroxidation products. Journal Of Applied Physiology 1989, 66: 2211-2215. PMID: 2787317, DOI: 10.1152/jappl.1989.66.5.2211.Peer-Reviewed Original ResearchMeSH KeywordsAlpha 1-AntitrypsinAntioxidantsBlood ProteinsDithiothreitolHumansKineticsLinoleic AcidLinoleic AcidsLipid BilayersLipid PeroxidationLipid PeroxidesMagnesiumMagnesium ChlorideMethionine Sulfoxide ReductasesOxidation-ReductionOxidoreductasesPancreatic ElastaseProtease InhibitorsStearic AcidsConceptsInhibitory capacityBronchoalveolar lavage fluidElastase inhibitory capacityLipid peroxidation productsElastase inhibitory activityMethionine sulfoxide peptide reductaseLinoleic acidLavage fluidVivo exposureAlpha-tocopherolOxidation of alphaPeroxidation productsGlutathione peroxidaseInhibitory effectLipid peroxidationAlphaInhibitory activityExogenous oxidantsInhibitorsVivoLipidsInhibitory siteStearic acid
1987
Acute Effect of Nitrogen Dioxide Exposure on the Functional Activity of Alpha-1-Protease Inhibitor in Bronchoalveolar Lavage Fluid of Normal Subjects
Mohsenin V, Gee J. Acute Effect of Nitrogen Dioxide Exposure on the Functional Activity of Alpha-1-Protease Inhibitor in Bronchoalveolar Lavage Fluid of Normal Subjects. American Journal Of Respiratory And Critical Care Medicine 1987, 136: 646-650. PMID: 3498415, DOI: 10.1164/ajrccm/136.3.646.Peer-Reviewed Original ResearchConceptsBronchoalveolar lavage fluidAlpha-1-protease inhibitorAlpha 1PILavage fluidControl subjectsFunctional activityLower respiratory tract fluidRespiratory tract fluidHuman leukocyte elastaseNitrogen dioxide exposureSignificant differencesEnd of exposureImmunoreactive alpha 1PIBronchoalveolar lavageNeutrophil migrationAcute effectsIntermittent exerciseNormal subjectsCigarette smokeControl groupHLE activityBALNO2 exposureNonsmokersLeukocyte elastase