Airway responsiveness and prostaglandin generation in scorbutic guinea pigs.
Mohsenin V, Tremml P, Rothberg K, Souhrada M, Douglas J. Airway responsiveness and prostaglandin generation in scorbutic guinea pigs. Prostaglandins Leukotrienes And Essential Fatty Acids 1988, 33: 149-55. PMID: 3186781.Peer-Reviewed Original ResearchConceptsAirway smooth muscleAirway hyperresponsivenessProstaglandin generationGuinea pigsAirway responsivenessHistamine aerosolSmooth muscleScorbutic guinea pigsAscorbic acid-deficient dietSignificant airway hyperresponsivenessScorbutic animalsSodium pump activityElectrogenic sodium pump activityAscorbic acid deficiencyProstanoid generationLung parenchymaDeficient dietElectrophysiological characteristicsControl animalsHyperresponsivenessAcid deficiencyControl groupElectrophysiological propertiesScorbutic conditionLung