1991
Lipid peroxidation and antielastase activity in the lung under oxidant stress: role of antioxidant defenses
Mohsenin V. Lipid peroxidation and antielastase activity in the lung under oxidant stress: role of antioxidant defenses. Journal Of Applied Physiology 1991, 70: 1456-1462. PMID: 2055821, DOI: 10.1152/jappl.1991.70.4.1456.Peer-Reviewed Original ResearchConceptsElastase inhibitory capacityAlveolar lining fluidLipid peroxidation productsLining fluidLavage fluidVitamin-supplemented groupOxidant stressLipid peroxidationPeroxidation productsControl groupLower respiratory tract fluidFour-week supplementationVitamin CRespiratory tract fluidNO2 exposureInactivation of alphaConjugated dienesVitamin supplementationNormal subjectsAntielastase activityInhibitory capacityOxidant exposureSignificant decreaseAntioxidant defensePeroxidation
1988
Airway responsiveness and prostaglandin generation in scorbutic guinea pigs.
Mohsenin V, Tremml P, Rothberg K, Souhrada M, Douglas J. Airway responsiveness and prostaglandin generation in scorbutic guinea pigs. Prostaglandins Leukotrienes And Essential Fatty Acids 1988, 33: 149-55. PMID: 3186781.Peer-Reviewed Original ResearchConceptsAirway smooth muscleAirway hyperresponsivenessProstaglandin generationGuinea pigsAirway responsivenessHistamine aerosolSmooth muscleScorbutic guinea pigsAscorbic acid-deficient dietSignificant airway hyperresponsivenessScorbutic animalsSodium pump activityElectrogenic sodium pump activityAscorbic acid deficiencyProstanoid generationLung parenchymaDeficient dietElectrophysiological characteristicsControl animalsHyperresponsivenessAcid deficiencyControl groupElectrophysiological propertiesScorbutic conditionLung
1987
Acute Effect of Nitrogen Dioxide Exposure on the Functional Activity of Alpha-1-Protease Inhibitor in Bronchoalveolar Lavage Fluid of Normal Subjects
Mohsenin V, Gee J. Acute Effect of Nitrogen Dioxide Exposure on the Functional Activity of Alpha-1-Protease Inhibitor in Bronchoalveolar Lavage Fluid of Normal Subjects. American Journal Of Respiratory And Critical Care Medicine 1987, 136: 646-650. PMID: 3498415, DOI: 10.1164/ajrccm/136.3.646.Peer-Reviewed Original ResearchConceptsBronchoalveolar lavage fluidAlpha-1-protease inhibitorAlpha 1PILavage fluidControl subjectsFunctional activityLower respiratory tract fluidRespiratory tract fluidHuman leukocyte elastaseNitrogen dioxide exposureSignificant differencesEnd of exposureImmunoreactive alpha 1PIBronchoalveolar lavageNeutrophil migrationAcute effectsIntermittent exerciseNormal subjectsCigarette smokeControl groupHLE activityBALNO2 exposureNonsmokersLeukocyte elastase