2021
Estimating incidence of infection from diverse data sources: Zika virus in Puerto Rico, 2016
Quandelacy T, Healy J, Greening B, Rodriguez D, Chung K, Kuehnert M, Biggerstaff B, Dirlikov E, Mier-y-Teran-Romero L, Sharp T, Waterman S, Johansson M. Estimating incidence of infection from diverse data sources: Zika virus in Puerto Rico, 2016. PLOS Computational Biology 2021, 17: e1008812. PMID: 33784311, PMCID: PMC8034731, DOI: 10.1371/journal.pcbi.1008812.Peer-Reviewed Original ResearchConceptsGuillain-Barré syndrome casesBlood bank dataIncidence of infectionZika virus epidemicSubset of casesSyndrome casesWeekly infectionsUnderlying incidenceZika virusArboviral casesInfectionSurveillance dataEpidemic preparednessZika epidemicVirus epidemicEpidemicIncidenceLarge proportionCasesWeeks
2020
Epidemiologic and spatiotemporal trends of Zika Virus disease during the 2016 epidemic in Puerto Rico
Sharp T, Quandelacy T, Adams L, Aponte J, Lozier M, Ryff K, Flores M, Rivera A, Santiago G, Muñoz-Jordán J, Alvarado L, Rivera-Amill V, Garcia-Negrón M, Waterman S, Paz-Bailey G, Johansson M, Rivera-Garcia B. Epidemiologic and spatiotemporal trends of Zika Virus disease during the 2016 epidemic in Puerto Rico. PLOS Neglected Tropical Diseases 2020, 14: e0008532. PMID: 32956416, PMCID: PMC7529257, DOI: 10.1371/journal.pntd.0008532.Peer-Reviewed Original ResearchConceptsZIKV diseaseDisease casesZika virusZIKV infectionArboviral diseasesEvidence of infectionZika virus diseaseLaboratory-based surveillancePuerto Rico DepartmentPublic health authoritiesIgM ELISAZIKV epidemicHigh incidenceChikungunya virusLaboratory evidenceHealth authoritiesDiseaseEarly detectionRT-PCRInfectionSocioeconomic factorsVirus diseaseEpidemicEarlier midpointIncidence
2016
Early Indicators of Fatal Leptospirosis during the 2010 Epidemic in Puerto Rico
Sharp TM, García B, Pérez-Padilla J, Galloway RL, Guerra M, Ryff KR, Haberling D, Ramakrishnan S, Shadomy S, Blau D, Tomashek KM, Bower WA. Early Indicators of Fatal Leptospirosis during the 2010 Epidemic in Puerto Rico. PLOS Neglected Tropical Diseases 2016, 10: e0004482. PMID: 26914210, PMCID: PMC4767218, DOI: 10.1371/journal.pntd.0004482.Peer-Reviewed Original ResearchConceptsFirst medical visitWhite blood cellsLeptospirosis patientsFatal outcomeMedical visitsFatal leptospirosisLaboratory valuesHospitalized leptospirosis patientsNon-fatal patientsRoutine laboratory valuesLeg painControl patientsMost patientsCase patientsHospital admissionMultivariable analysisIllness onsetPlatelet countDengue patientsFatal casesWBC countLeptospirosis epidemicPatientsMedical careOld male