2023
Identification of risk factors and mosquito vectors associated with dengue virus infection in American Samoa, 2017
Sharp T, Tufa A, Cotter C, Lozier M, Santiago G, Johnson S, Mataia’a M, Waterman S, Muñoz-Jordán J, Paz-Bailey G, Hemme R, Schmaedick M, Anesi S. Identification of risk factors and mosquito vectors associated with dengue virus infection in American Samoa, 2017. PLOS Global Public Health 2023, 3: e0001604. PMID: 37418355, PMCID: PMC10328243, DOI: 10.1371/journal.pgph.0001604.Peer-Reviewed Original ResearchDENV infectionIgM ELISARisk factorsRT-PCRDENV-2Dengue virus infectionPopulation-specific risk factorsFrequency of infectionDENV nucleic acidMosquito vectorsOutbreak of dengueCluster investigationsFebrile illnessMedian ageResidents of householdsRole of AeDengue patientsVirus infectionDENV transmissionSerum specimensZika virusPatient specimensBivariate analysisInfectionAdult female mosquitoes
2020
Epidemiologic and spatiotemporal trends of Zika Virus disease during the 2016 epidemic in Puerto Rico
Sharp T, Quandelacy T, Adams L, Aponte J, Lozier M, Ryff K, Flores M, Rivera A, Santiago G, Muñoz-Jordán J, Alvarado L, Rivera-Amill V, Garcia-Negrón M, Waterman S, Paz-Bailey G, Johansson M, Rivera-Garcia B. Epidemiologic and spatiotemporal trends of Zika Virus disease during the 2016 epidemic in Puerto Rico. PLOS Neglected Tropical Diseases 2020, 14: e0008532. PMID: 32956416, PMCID: PMC7529257, DOI: 10.1371/journal.pntd.0008532.Peer-Reviewed Original ResearchConceptsZIKV diseaseDisease casesZika virusZIKV infectionArboviral diseasesEvidence of infectionZika virus diseaseLaboratory-based surveillancePuerto Rico DepartmentPublic health authoritiesIgM ELISAZIKV epidemicHigh incidenceChikungunya virusLaboratory evidenceHealth authoritiesDiseaseEarly detectionRT-PCRInfectionSocioeconomic factorsVirus diseaseEpidemicEarlier midpointIncidence
2017
Risk Factors Associated with Persistence of Zika Virus Nucleic Acid in Serum and Semen
Lozier M, Rosenberg E, Doyle K, Adams L, Klein L, Muñoz-Jordan J, Alvarado L, Sharp T, Paz-Bailey G. Risk Factors Associated with Persistence of Zika Virus Nucleic Acid in Serum and Semen. Open Forum Infectious Diseases 2017, 4: s56-s57. PMCID: PMC5632286, DOI: 10.1093/ofid/ofx162.133.Peer-Reviewed Original ResearchDetectable ZIKV RNADays post-symptom onsetLonger median timeNon-pregnant womenZIKV RNAPregnant womenSymptom onsetMedian timeStudy participationRT-PCRPost-symptom onsetDuration of detectionRT-PCR testingZika virus RNAProportion of menVirus nucleic acidZika virus nucleic acidProspective cohortPrevention recommendationsRisk factorsIndex caseDiagnostic testingFirst monthConjunctivitisSerumPersistence of Zika Virus in Body Fluids — Final Report
Paz-Bailey G, Rosenberg ES, Doyle K, Munoz-Jordan J, Santiago GA, Klein L, Perez-Padilla J, Medina FA, Waterman SH, Adams L, Lozier M, Bertrán-Pasarell J, Garcia Gubern C, Alvarado L, Sharp T. Persistence of Zika Virus in Body Fluids — Final Report. New England Journal Of Medicine 2017, 379: 1234-1243. PMID: 28195756, PMCID: PMC5831142, DOI: 10.1056/nejmoa1613108.Peer-Reviewed Original ResearchZIKV RNAZIKV RNA detectionVaginal secretionsIgM enzyme-linked immunosorbentDetectable ZIKV RNARNA detectionZika virus RNAEnzyme-linked immunosorbentZIKV exposureZIKV infectionWeek 4RNA clearanceZika virusSurveillance sitesFirst monthRT-PCRSerumVirus RNAMonthsBody fluidsUrineSecretionDaysMedianRegression models